The Effect of a Short Term Meditation Retreat on Markers of Cellular Stress and Aging
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 96
- 试验地点
- 2
- 主要终点
- Telomerase
研究概览
简要总结
The purpose of this research study is to examine whether a short term meditation intervention can improve health, mood, and biological markers of cellular stress and aging in novice and experienced meditators compared to controls.
详细描述
There are 3 parts to this research study, Part A, B, and C.
In Part A, participants complete a brief online questionnaire sent to them via email by the study coordinator.
During Part B of the study, participants stay at La Costa Resort in Carlsbad, CA for 6 nights and participate in a meditation retreat being held at the resort, or stay at the resort without participating in the retreat. During their stay, participants attend two in-person research assessments throughout the week. Assessments will be 4 days (96 hours) apart for all participants and will include a fasting blood draw, body measurements, and self-report questionnaires.
Part C of the study includes a brief online questionnaire that is completed 1 month after participants leave La Costa Resort.
This study includes 3 groups: a group of "novice meditators" from the greater San Diego Region that are randomized into either the 1) Relaxation (Control) group or 2) Retreat group. The third group is comprised of self-selected "experienced meditators" who are already enrolled in the retreat. In total, 99 participants were recruited for this study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 30 Years 至 60 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Age 30-60
- •"Novice Meditator" (meditates for 30 minutes per week or less) or "Experienced Meditator" (meditates at 40 or more per week and for more than 6 months, and are self-selected/enrolled in the retreat)
排除标准
- •Current or history of a major medical condition (such as cancer, heart disease, autoimmune disease, diabetes)
- •Smokers (have not smoked regularly for the past 6 months)
- •Currently taking antidepressants
- •Post Traumatic Stress Disorder
- •Currently taking Hormone Replacement Therapy or birth control pills
结局指标
主要结局
Telomerase
时间窗: Change from Baseline in Telomerase 96 hours later
Participants blood will be drawn by licensed phlebotomist on the day after their arrival at La Costa Resort at their baseline assessment and again 96 hours later at their follow-up assessment. Telomerase will be measured at both time points.
次要结局
- Amyloid Beta Proteins(Change from baseline in Amyloid Beta Proteins, 96 hours later)
- Psychological Well being(Change from Baseline in psychological well being at 96 hours, and 1 month later.)
- Oxytocin(Change from baseline in Oxytocin at 96 hours later.)
- Telomere Length(Change from Baseline in Telomere Length, 96 hours later)
- Gene Expression(Change from Baseline in Gene Expression, 96 hours later)