The effect of resistance exercise on muscle in advanced-stage ovarian cancer survivors who have completed first line treatment: A pilot randomised controlled trial

Not Applicable

Recruiting

• Conditions: Ovarian cancer; Cancer - Ovarian and primary peritoneal; Physical Medicine / Rehabilitation - Other physical medicine / rehabilitation

• Registration Number: ACTRN12619000261112
• Lead Sponsor: Edith Cowan University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-02-20
• Last Update Posted: 24 February 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 40

Inclusion Criteria

Women with histologically confirmed stages III and IV epithelial ovarian cancer who have completed first-line surgical and chemotherapy treatment at least four weeks and no more than three months prior to participation.

Exclusion Criteria

(1) age younger than 18 years,
(2) inability to obtain approval from the treating gynaecological or medical oncologist or general practitioner,
(3) inability to understand and speak English,
(4) on anti- angiogenetic (Bevacizumab) treatment,
(5) recurrent ovarian cancer,
(6) existing or suspected bone metastasis,
(7) acute illness or any musculoskeletal, cardiovascular or neurological disorder that could put participants at risk during exercise testing or exercise training, as determined by their specialist or general practitioner.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Muscle mass as assessed with dual-energy x-ray absorptiometry (DEXA) and peripheral quantitative computed tomography (pQCT) scans [Baseline and one to two weeks after completion of 12-week intervention (primary timepoint)];Muscle density as assessed with peripheral quantitative computed tomography (pQCT) scans[Baseline and one to two weeks after completion of 12-week intervention (primary timepoint)]