NCT03281928TerminatedNot Applicable
Effect of Dietary Sodium and Potassium Citrate on Renal Mineral Handling
Conditions
Interventions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Terminated
- Sponsor
- University of Chicago
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Urine Calcium levels
Study Overview
Brief Summary
This study intends to characterize the affect of sodium and potassium citrate in the diet on renal function.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Other
- Masking
- Double (Investigator, Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to 70 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •age 18 - 70, approximately equal numbers of men and women
- •studied by endoscopy with complete papillary mapping and grading
- •stone formers
Exclusion Criteria
- •Patients with primary renal diseases or renal impairment (eGFR < 90), or medical conditions such as diabetes, or systemic diseases or medications that alter calcium metabolism
- •Patients with known bladder voiding problems
Arms & Interventions
High Sodium plus placebo
Placebo Comparator
Intervention: Placebo (Dietary Supplement)
Low Sodium plus Potassium Citrate
Experimental
Intervention: Sodium and Potassium Citrate (Dietary Supplement)
Low Sodium plus placebo
Placebo Comparator
Intervention: Placebo (Dietary Supplement)
High Sodium plus Potassium Citrate
Experimental
Intervention: Sodium and Potassium Citrate (Dietary Supplement)
Outcomes
Primary Outcomes
Urine Calcium levels
Time Frame: 10 days
Amount of calcium in the urine will be measured
Secondary Outcomes
No secondary outcomes reported
Investigators
Study Sites (1)
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