Exercise and Health Intervention for Patients With Obsessive Compulsive Disorder (OCD)

Phase 2

Completed

• Conditions: Obsessive Compulsive Disorder
• Interventions: Behavioral: Health and Wellness; Behavioral: Aerobic exercise

• Registration Number: NCT01242735
• Lead Sponsor: Butler Hospital

Brief Summary

The purpose of this study is to test the effect of a moderate-intensity aerobic exercise intervention for Obsessive Compulsive Disorder (OCD) patients interested in reducing symptoms. The investigators expect that this project will contribute much needed knowledge about the role that aerobic exercise can play in managing the effects of OCD. If moderate-intensity aerobic exercise is efficacious in helping individuals with OCD manage obsessions and compulsions, this will establish that aerobic exercise may be a valuable adjunct to other OCD treatments such as medication and therapy.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-11
• Study First Submitted: 2010-11-16
• Study First Submitted QC: 2010-11-16
• Study First Posted: 2010-11-17
• Primary Completion: 2015-03
• Study Completion: 2015-03
• Status Verified: 2015-07
• Last Update Submitted: 2015-07-21
• Last Update Posted: 2015-07-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 56

Inclusion Criteria

1. are between 18 and 65 years of age
2. are sedentary, i.e. have not participated in regular aerobic physical exercise for at least 90 minutes per week during the past three months
3. currently engaged in at least 12 weeks of stable dose pharmacotherapy and/or are currently engaged in cognitive-behavioral therapy for the past 13 weeks
4. meet Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV) criteria for OCD as assessed by the Structured Clinical Interview for DSM Disorders, Patient Version (SCID-P)
5. have Y-BOCS score greater than 16

Exclusion Criteria

1. DSM-IV diagnosis of substance abuse/dependence except for nicotine dependence
2. DSM-IV diagnosis of anorexia or bulimia nervosa
3. DSM-IV diagnosis of bipolar disorder
4. history of psychotic disorder or current psychotic symptoms
5. current suicidality or homicidality
6. marked organic impairment
7. physical or medical problems that would not allow for safe exercise participation
8. current pregnancy or intent to become pregnant during the next 12 weeks

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Health and Wellness	Health and Wellness	12-week health and wellness education control (HEC)
Exercise	Aerobic exercise	12-week moderate-intensity behavioral exercise intervention (AE)

Primary Outcome Measures

Name	Time	Method
Yale-Brown Obsessive Compulsive Scale (Y-BOCS; OCD symptomatology)	15 months

Trial Locations

Locations (1)

Butler Hospital; 🇺🇸 Providence, Rhode Island, United States