Intramuscular Versus Intravenous Prophylactic Oxytocin for the Third Stage of Labour Following Vaginal Delivery: A Randomised Controlled Trial
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 2
- 试验地点
- 1
- 主要终点
- early postpartum hemorrhage
研究概览
简要总结
Intramuscular versus intravenous prophylactic oxytocin for the third stage of labour following vaginal delivery: A randomised controlled trial
详细描述
Prevention of postpartum haemorrhage is essential in the pursuit of improved health care for women. In this study investigators aimed to compare intramuscular oxytocin with intravenous oxytocin for the routine prevention of postpartum haemorrhage in women who deliver vaginally.In some countries, intravenous access can not be provided easily . Intramuscular application is faster , easier and tougher enforcement requires less skill and equipment . For this reason, less educated , which can be applied by those offering health services .
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Research volunteers, the undersigned, pregnant women
- •Only with vaginal delivery (episiotomy and perineal tears can)
- •> 34 weeks or more will be
- •Cephalic presentation will be
- •At low risk of postpartum hemorrhage
排除标准
- •Multiple pregnancies
- •The presence of uterine myoma
- •Having postpartum hemorrhage in previous pregnancies
- •Placenta previa, polyhydramnios
- •More than four parity
- •Fetal macrosomia
- •Hb <9mg/dl
- •preeclampsia
- •Uterine anomalies
- •Receiving anticoagulant therapy, suspected coagulopathy
- •> 42 weeks of pregnancy
- •Oxytocin allergy -
研究组 & 干预措施
intravenous 10 ıu oxytocin
group which 2 ampul prophylactic oxytocin given for third stage of labour intravenously after vaginal delivery
干预措施: intarvenous and intramusculer 10 IU oxytocin (Drug)
intramusculer 10 ıu oxytocin
group which oxytocin administered intramusculary after vaginal delivery
干预措施: intarvenous and intramusculer 10 IU oxytocin (Drug)
结局指标
主要结局
early postpartum hemorrhage
时间窗: postpartum 24 hours
Blood loss during the birth and postpartum hemorrhage asset (within 24 hours\> 500 cc blood loss)
次要结局
- Blood transfusion requirement(postpartum 24 hours)
研究者
Hediye Dagdeviren
md
Bakirkoy Dr. Sadi Konuk Research and Training Hospital