Alveolar Ridge Augmentation Following Tooth Extraction Using Bovine Xenograft With Platelet Rich Fibrin Membrane

Not Applicable

Completed

• Conditions: Bone Regeneration
• Interventions: Procedure: a bone graft mixed with PRF & covered by PRF membrane in fresh extraction socket

• Registration Number: NCT05791123
• Lead Sponsor: Future University in Egypt

Brief Summary

fourteen patients requiring extraction of one posterior tooth with lost buccal bone (\>50%) confirmed preoperatively by Cone-beam computed tomography (CBCT) scans. Extraction sockets were filled with minced PRF clots mixed with the bovine xenograft and covered by PRF membranes to seal the extraction sockets. (CBCT) scans, performed before tooth extraction and after 6 months, were used to assess vertical and horizontal bone changes.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-07-15
• Primary Completion: 2023-02-20
• Status Verified: 2023-03
• Study Completion: 2023-03-05
• Study First Submitted: 2023-03-08
• Study First Submitted QC: 2023-03-17
• Last Update Submitted: 2023-03-17
• Study First Posted: 2023-03-30
• Last Update Posted: 2023-03-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 14

Inclusion Criteria

• Patients required implant treatment after tooth extraction
• Age group ranged from 20-60 years old.
• Patients could undergo the treatment under local anesthesia.
• Loss of buccal bone (>50%) confirmed by preoperative cone beam computed tomography (CBCT).
• Presence of other socket walls; mesial, distal and lingual walls.
• Tooth needed to be extracted in upper or lower posterior regions

Exclusion Criteria

• Uncontrolled diabetic diseases.
• Uncontrolled hypertension, or hepatic and renal disorders.
• Any systemic diseases associated with bone metabolism.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
a bone graft mixed with PRF & covered by PRF membrane in fresh extraction socket	a bone graft mixed with PRF & covered by PRF membrane in fresh extraction socket	-

Primary Outcome Measures

Name	Time	Method
the change in alveolar bone width and height in mm using CBCT scans.	6 months	Cone Beam Computed Tomography were taken for each patients before tooth extraction and after 6 months, which were used to assess alveolar ridge changes in width and length in mm.

Trial Locations

Locations (1)

Future University in Egypt; 🇪🇬 Cairo, Egypt