MedPath

Testing the Addition of Ruxolitinib to the Usual Treatment (Tyrosine Kinase Inhibitors) for Chronic Myeloid Leukemia

Phase 2
Active, not recruiting
Conditions
Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
Interventions
Registration Number
NCT03654768
Lead Sponsor
SWOG Cancer Research Network
Brief Summary

This randomized phase II trial studies how well ruxolitinib phosphate, and bosutnib, dasatinib, imatinib or nilotinib, work in treating patients with chronic myeloid leukemia. Chronic myeloid leukemia cells produce a protein called BCR-ABL. The BCR-ABL protein helps chronic myeloid leukemia cells to grow and divide. Tyrosine kinase inhibitors, such as bosutinib, dasatinib, and nilotinib, stop the BCR-ABL protein from working, which helps to reduce the amount of chronic myeloid leukemia cells in the body. Ruxolitinib is a different type of drug that helps to stop the body from making substances called growth factors. Chronic myeloid leukemia cells need growth factors to grow and divide. The addition of ruxolitinib to the tyrosine kinase inhibitor may or may not help reduce the amount of chronic myeloid leukemia cells in the body.

Detailed Description

PRIMARY OBJECTIVE:

I. To compare the rate of molecular response 4.5 (MR4.5) after 12 months of combination therapy with ruxolitinib phosphate (ruxolitinib) plus a tyrosine-kinase inhibitor (TKI) (bosutinib, dasatinib, imatinib or nilotinib) versus a TKI alone, based on local polymerase chain reaction (PCR) testing to measure BCR-ABL transcripts in chronic phase chronic myelogenous leukemia (CML) patients with molecular evidence of disease.

SECONDARY OBJECTIVES:

I. To estimate the frequency and severity of toxicities of each regimen in this patient population.

II. To estimate progression free survival and overall survival of each regimen in this patient population.

ADDITIONAL OBJECTIVES:

I. To describe patterns of MR4.5 and molecular response 4.0 (MR4.0) attainment and failure over the 3, 6, 9, and 12-month time points of each regimen in this patient population.

II. To evaluate drug compliance based on patient reported drug intake calendars in this patient population.

III. To describe the kinetics of response in this patient population (as measured by quantitative BCR-ABL/BCR ratio) in both arms over the 3, 6, 9, and 12-month time points.

OUTLINE: Patients are randomized to 1 of 2 arms.

ARM I: Patients receive bosutinib orally (PO) daily or dasatinib PO daily or nilotinib PO twice daily (BID) or imatinib PO daily on days 1-90. Treatment repeats every 90 days for up to 4 cycles in the absence of disease progression or unacceptable toxicity.

ARM II: Patients receive ruxolitinib phosphate PO BID on days 1-90, and bosutinib PO daily or dasatinib PO daily or nilotinib PO BID or imatinib PO daily on days 1-90. Treatment repeats every 90 days for up to 4 cycles in the absence of disease progression or unacceptable toxicity.

After completion of study treatment, patients are followed up every 6 months for 2 years, and then annually up to 5 years.

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
84
Inclusion Criteria
  • Patients must have a diagnosis of chronic phase chronic myeloid leukemia without any history of progression to accelerated or blast phase CML; no new bone marrow aspiration and biopsy is needed to prove diagnosis prior to randomization; however, documentation stating the patient is in chronic phase is required
  • Patients must have detectable BCR-ABL transcripts measured by reverse transcriptase (RT)-PCR at a clinical laboratory improvement act (CLIA)-approved laboratory and reported on the international scale (IS) with a value of > 0.0032% IS and =< 1.0% IS within 21 days prior to randomization; the RT-PCR assay must have the sensitivity to detect a 4.5 log reduction in BCR-ABL transcripts from 100% IS (0.0032% IS or lower)
  • Patients must have been receiving TKI treatment for CML for at least 12 months prior to randomization. Hydroxyurea prior to initiation of TKI is allowed.
  • Patients must be currently receiving treatment with bosutinib (within the allowable dose range of 200-500 mg daily), nilotinib (within the allowable dose range of 150-400 mg BID or a cumulative daily dose of 300-800 mg), dasatinib (within the allowable dose range of 40-140 mg daily), or imatinib (within the allowable dose range of 300-400 mg daily); they must have received their current TKI for a minimum of 6 months prior to randomization and must be expected to remain on the same TKI for the next 12 months
  • Patient must not have a history of resistance to any prior TKI drug; if patient has received more than one TKI, the reason for changing treatment must have been something other than resistance or inadequate response to the prior TKI (for example, intolerance to the prior TKI) and the treatment change must have occurred >= 6 months prior to randomization.
  • Patients must not be receiving any other investigational agents
  • Patients must have complete history and physical examination within 28 days prior to randomization
  • If clinically indicated, patients must have corrected Fridericia's correction formula (QTcF) interval < 500 ms (by Fridericia calculation) on a 12-lead electrocardiography (EKG) within 7 days prior to randomization
  • Platelets >= 100,000/mm^3 (100.0 x 10^9/L) within 7 days prior to randomization
  • Absolute neutrophil count (ANC) > 1,000/mm^3 (1.0 x 10^9/L) within 7 days prior to randomization
  • Hemoglobin >= 8 g/dL within 7 days prior to randomization
  • Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) =< 2.5 x institutional upper limit of normal (IULN) within 7 days prior to randomization
  • Total bilirubin =< 1.5 x IULN within 7 days prior to randomization (unless the patient has a known diagnosis of Gilbert's syndrome)
  • Serum creatinine =< 1.5 x IULN within 7 days prior to randomization
  • Prior malignancy is allowed providing it does not require concurrent therapy; exception: active hormonal therapy is allowed
  • Patients must not be pregnant or nursing due to the teratogenic potential of the drugs used on this study; women of child-bearing potential must have a negative serum pregnancy test within 7 days prior to randomization; women/men of reproductive potential must have agreed to use an effective contraceptive method during treatment and for 30 days after discontinuation of study drug; a woman is considered to be of "reproductive potential" if she has had menses at any time in the preceding 12 consecutive months; in addition to routine contraceptive methods, "effective contraception" also includes heterosexual celibacy and surgery intended to prevent pregnancy (or with a side-effect of pregnancy prevention) defined as a hysterectomy, bilateral oophorectomy or bilateral tubal ligation; however, if at any point a previously celibate patient chooses to become heterosexually active during the time period for use of contraceptive measures outlined in the protocol, he/she is responsible for beginning contraceptive measures
  • Patients known to be human immunodeficiency virus positive (HIV+) are eligible provided they meet all other eligibility criteria and have undetectable HIV viral loads on their most recent viral load test which must have been performed in the last 6 months
  • Specimens (peripheral blood) must be collected and submitted to a CLIA-approved laboratory, within 21 days prior to randomization; BCR-ABL transcripts must be measured using RT-PCR and results must be reported using the international scale; the RT-PCR assay must have the sensitivity to detect a 4.5 log reduction in BCR-ABL transcripts from 100% IS (must be able to detect 0.0032% IS or lower)
  • Patients must be offered participation in submission of specimens for central BCR-ABL quantification and banking for future specimens; this submission is highly encouraged as an important protocol endpoint; with patient's consent, specimens must be collected and submitted, within 21 days prior to randomization
  • Patients must be informed of the investigational nature of this study and must sign and give written informed consent in accordance with institutional and federal guidelines
  • As a part of the Oncology Patient Enrollment Network (OPEN) registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system
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Exclusion Criteria

Not provided

Read More

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Arm I (bosutinib, dasatinib, nilotinib, imatinib)Laboratory Biomarker AnalysisPatients receive bosutinib PO daily or dasatinib PO daily or nilotinib PO BID or imatinib PO daily on days 1-90. Treatment repeats every 90 days for up to 4 cycles in the absence of disease progression or unacceptable toxicity.
Arm I (bosutinib, dasatinib, nilotinib, imatinib)DasatinibPatients receive bosutinib PO daily or dasatinib PO daily or nilotinib PO BID or imatinib PO daily on days 1-90. Treatment repeats every 90 days for up to 4 cycles in the absence of disease progression or unacceptable toxicity.
Arm I (bosutinib, dasatinib, nilotinib, imatinib)NilotinibPatients receive bosutinib PO daily or dasatinib PO daily or nilotinib PO BID or imatinib PO daily on days 1-90. Treatment repeats every 90 days for up to 4 cycles in the absence of disease progression or unacceptable toxicity.
Arm II (ruxolitinib phosphate, dasatinib, nilotinib, imatinib)Laboratory Biomarker AnalysisPatients receive ruxolitinib phosphate PO BID on days 1-90, and bosutinib PO daily or dasatinib PO daily or nilotinib PO BID or imatinib PO daily on days 1-90. Treatment repeats every 90 days for up to 4 cycles in the absence of disease progression or unacceptable toxicity.
Arm I (bosutinib, dasatinib, nilotinib, imatinib)BosutinibPatients receive bosutinib PO daily or dasatinib PO daily or nilotinib PO BID or imatinib PO daily on days 1-90. Treatment repeats every 90 days for up to 4 cycles in the absence of disease progression or unacceptable toxicity.
Arm I (bosutinib, dasatinib, nilotinib, imatinib)ImatinibPatients receive bosutinib PO daily or dasatinib PO daily or nilotinib PO BID or imatinib PO daily on days 1-90. Treatment repeats every 90 days for up to 4 cycles in the absence of disease progression or unacceptable toxicity.
Arm II (ruxolitinib phosphate, dasatinib, nilotinib, imatinib)DasatinibPatients receive ruxolitinib phosphate PO BID on days 1-90, and bosutinib PO daily or dasatinib PO daily or nilotinib PO BID or imatinib PO daily on days 1-90. Treatment repeats every 90 days for up to 4 cycles in the absence of disease progression or unacceptable toxicity.
Arm II (ruxolitinib phosphate, dasatinib, nilotinib, imatinib)NilotinibPatients receive ruxolitinib phosphate PO BID on days 1-90, and bosutinib PO daily or dasatinib PO daily or nilotinib PO BID or imatinib PO daily on days 1-90. Treatment repeats every 90 days for up to 4 cycles in the absence of disease progression or unacceptable toxicity.
Arm II (ruxolitinib phosphate, dasatinib, nilotinib, imatinib)RuxolitinibPatients receive ruxolitinib phosphate PO BID on days 1-90, and bosutinib PO daily or dasatinib PO daily or nilotinib PO BID or imatinib PO daily on days 1-90. Treatment repeats every 90 days for up to 4 cycles in the absence of disease progression or unacceptable toxicity.
Arm II (ruxolitinib phosphate, dasatinib, nilotinib, imatinib)ImatinibPatients receive ruxolitinib phosphate PO BID on days 1-90, and bosutinib PO daily or dasatinib PO daily or nilotinib PO BID or imatinib PO daily on days 1-90. Treatment repeats every 90 days for up to 4 cycles in the absence of disease progression or unacceptable toxicity.
Primary Outcome Measures
NameTimeMethod
Rate of molecular response 4.5 (MR4.5)At 12 months
Secondary Outcome Measures
NameTimeMethod
MR4.5 attainment and failureUp to 12 months

Will be summarized descriptively

Overall survivalFrom the date of randomization until death from any cause with observations censored at the date of last contact for patients last known to be alive, assessed up to 5 years

Will be estimated using the Kaplan-Meier method.

Progression-free survivalFrom the date of randomization on study until the first of treatment failure/loss of response, progression, or death from any cause, assessed up to 5 years

Will be estimated using the Kaplan-Meier method.

Molecular rate 4.0 (MR 4.0) attainment and failureUp to 12 months

Will be summarized descriptively

Incidence of adverse eventsUp to 5 years

Will be assessed by National Cancer Institute Common Terminology Criteria for Adverse Events (CTCAE) version 4.0. CTCAE version 5.0 will be utilized for serious adverse events reporting only.

Drug complianceUp to 5 years

Will be summarized descriptively

BCR-ABL/BCR analysisUp to 5 years

Linear regression models will be used to assess associations between treatment arm and the quantitative endpoint.

Trial Locations

Locations (540)

Anchorage Associates in Radiation Medicine

🇺🇸

Anchorage, Alaska, United States

Anchorage Radiation Therapy Center

🇺🇸

Anchorage, Alaska, United States

Alaska Breast Care and Surgery LLC

🇺🇸

Anchorage, Alaska, United States

Alaska Oncology and Hematology LLC

🇺🇸

Anchorage, Alaska, United States

Anchorage Oncology Centre

🇺🇸

Anchorage, Alaska, United States

Katmai Oncology Group

🇺🇸

Anchorage, Alaska, United States

Providence Alaska Medical Center

🇺🇸

Anchorage, Alaska, United States

Mercy Hospital Fort Smith

🇺🇸

Fort Smith, Arkansas, United States

CHI Saint Vincent Cancer Center Hot Springs

🇺🇸

Hot Springs, Arkansas, United States

Mission Hope Medical Oncology - Arroyo Grande

🇺🇸

Arroyo Grande, California, United States

PCR Oncology

🇺🇸

Arroyo Grande, California, United States

Providence Saint Joseph Medical Center/Disney Family Cancer Center

🇺🇸

Burbank, California, United States

Providence Queen of The Valley

🇺🇸

Napa, California, United States

Pacific Central Coast Health Center-San Luis Obispo

🇺🇸

San Luis Obispo, California, United States

Mission Hope Medical Oncology - Santa Maria

🇺🇸

Santa Maria, California, United States

Providence Medical Foundation - Santa Rosa

🇺🇸

Santa Rosa, California, United States

Providence Santa Rosa Memorial Hospital

🇺🇸

Santa Rosa, California, United States

Boulder Community Hospital

🇺🇸

Boulder, Colorado, United States

Boulder Community Foothills Hospital

🇺🇸

Boulder, Colorado, United States

Rocky Mountain Cancer Centers-Boulder

🇺🇸

Boulder, Colorado, United States

Rocky Mountain Cancer Centers - Centennial

🇺🇸

Centennial, Colorado, United States

Penrose-Saint Francis Healthcare

🇺🇸

Colorado Springs, Colorado, United States

Rocky Mountain Cancer Centers-Penrose

🇺🇸

Colorado Springs, Colorado, United States

Saint Francis Cancer Center

🇺🇸

Colorado Springs, Colorado, United States

Mercy Medical Center

🇺🇸

Springfield, Massachusetts, United States

Southwest Oncology PC

🇺🇸

Durango, Colorado, United States

Rocky Mountain Cancer Centers - Swedish

🇺🇸

Englewood, Colorado, United States

Swedish Medical Center

🇺🇸

Englewood, Colorado, United States

The Melanoma and Skin Cancer Institute

🇺🇸

Englewood, Colorado, United States

Mountain Blue Cancer Care Center

🇺🇸

Golden, Colorado, United States

National Jewish Health-Western Hematology Oncology

🇺🇸

Golden, Colorado, United States

North Colorado Medical Center

🇺🇸

Greeley, Colorado, United States

Saint Mary's Hospital and Regional Medical Center

🇺🇸

Grand Junction, Colorado, United States

Good Samaritan Medical Center

🇺🇸

Lafayette, Colorado, United States

Rocky Mountain Cancer Centers-Lakewood

🇺🇸

Lakewood, Colorado, United States

Saint Anthony Hospital

🇺🇸

Lakewood, Colorado, United States

Rocky Mountain Cancer Centers-Littleton

🇺🇸

Littleton, Colorado, United States

Littleton Adventist Hospital

🇺🇸

Littleton, Colorado, United States

Rocky Mountain Cancer Centers-Sky Ridge

🇺🇸

Lone Tree, Colorado, United States

Sky Ridge Medical Center

🇺🇸

Lone Tree, Colorado, United States

Longmont United Hospital

🇺🇸

Longmont, Colorado, United States

Rocky Mountain Cancer Centers-Longmont

🇺🇸

Longmont, Colorado, United States

McKee Medical Center

🇺🇸

Loveland, Colorado, United States

Parker Adventist Hospital

🇺🇸

Parker, Colorado, United States

Rocky Mountain Cancer Centers-Parker

🇺🇸

Parker, Colorado, United States

Rocky Mountain Cancer Centers - Pueblo

🇺🇸

Pueblo, Colorado, United States

Saint Mary Corwin Medical Center

🇺🇸

Pueblo, Colorado, United States

National Jewish Health-Northern Hematology Oncology

🇺🇸

Thornton, Colorado, United States

Rocky Mountain Cancer Centers-Thornton

🇺🇸

Thornton, Colorado, United States

SCL Health Lutheran Medical Center

🇺🇸

Wheat Ridge, Colorado, United States

Holy Cross Hospital

🇺🇸

Fort Lauderdale, Florida, United States

Fairview Ridges Hospital

🇺🇸

Burnsville, Minnesota, United States

West Michigan Cancer Center

🇺🇸

Kalamazoo, Michigan, United States

Great Lakes Cancer Management Specialists-Macomb Medical Campus

🇺🇸

Macomb, Michigan, United States

Newland Medical Associates-Pontiac

🇺🇸

Pontiac, Michigan, United States

Minnesota Oncology - Burnsville

🇺🇸

Burnsville, Minnesota, United States

Saint Mary's Oncology/Hematology Associates of Marlette

🇺🇸

Marlette, Michigan, United States

Genesys Hurley Cancer Institute

🇺🇸

Flint, Michigan, United States

Bronson Methodist Hospital

🇺🇸

Kalamazoo, Michigan, United States

Unity Hospital

🇺🇸

Fridley, Minnesota, United States

Ascension Borgess Cancer Center

🇺🇸

Kalamazoo, Michigan, United States

Lakeland Hospital Niles

🇺🇸

Niles, Michigan, United States

Sparrow Hospital

🇺🇸

Lansing, Michigan, United States

Fairview Southdale Hospital

🇺🇸

Edina, Minnesota, United States

Cancer and Hematology Centers of Western Michigan - Norton Shores

🇺🇸

Norton Shores, Michigan, United States

Monticello Cancer Center

🇺🇸

Monticello, Minnesota, United States

Lakeview Hospital

🇺🇸

Stillwater, Minnesota, United States

Lakeland Medical Center Saint Joseph

🇺🇸

Saint Joseph, Michigan, United States

Park Nicollet Clinic - Saint Louis Park

🇺🇸

Saint Louis Park, Minnesota, United States

Hope Cancer Center

🇺🇸

Pontiac, Michigan, United States

Southeast Cancer Center

🇺🇸

Cape Girardeau, Missouri, United States

Huron Gastroenterology PC

🇺🇸

Ypsilanti, Michigan, United States

Great Lakes Cancer Management Specialists-Macomb Professional Building

🇺🇸

Warren, Michigan, United States

Cambridge Medical Center

🇺🇸

Cambridge, Minnesota, United States

Saint Louis Cancer and Breast Institute-Ballwin

🇺🇸

Ballwin, Missouri, United States

Saint John Macomb-Oakland Hospital

🇺🇸

Warren, Michigan, United States

Mercy Hospital

🇺🇸

Coon Rapids, Minnesota, United States

Central Care Cancer Center - Bolivar

🇺🇸

Bolivar, Missouri, United States

Saint John's Hospital - Healtheast

🇺🇸

Maplewood, Minnesota, United States

Baptist Memorial Hospital and Cancer Center-Oxford

🇺🇸

Oxford, Mississippi, United States

Regions Hospital

🇺🇸

Saint Paul, Minnesota, United States

Cox Cancer Center Branson

🇺🇸

Branson, Missouri, United States

Minnesota Oncology Hematology PA-Maplewood

🇺🇸

Maplewood, Minnesota, United States

Fairview Clinics and Surgery Center Maple Grove

🇺🇸

Maple Grove, Minnesota, United States

United Hospital

🇺🇸

Saint Paul, Minnesota, United States

Mercy Hospital South

🇺🇸

Saint Louis, Missouri, United States

CHI Health Good Samaritan

🇺🇸

Kearney, Nebraska, United States

Kalispell Regional Medical Center

🇺🇸

Kalispell, Montana, United States

University of New Mexico Cancer Center

🇺🇸

Albuquerque, New Mexico, United States

Margaret R Pardee Memorial Hospital

🇺🇸

Hendersonville, North Carolina, United States

Columbus Oncology and Hematology Associates

🇺🇸

Dublin, Ohio, United States

Licking Memorial Hospital

🇺🇸

Newark, Ohio, United States

Delaware Health Center-Grady Cancer Center

🇺🇸

Delaware, Ohio, United States

Saint Rita's Medical Center

🇺🇸

Lima, Ohio, United States

Toledo Clinic Cancer Centers-Maumee

🇺🇸

Maumee, Ohio, United States

Roswell Park Cancer Institute

🇺🇸

Buffalo, New York, United States

Sanford South University Medical Center

🇺🇸

Fargo, North Dakota, United States

Strecker Cancer Center-Belpre

🇺🇸

Belpre, Ohio, United States

Adena Regional Medical Center

🇺🇸

Chillicothe, Ohio, United States

Mount Carmel East Hospital

🇺🇸

Columbus, Ohio, United States

Grant Medical Center

🇺🇸

Columbus, Ohio, United States

Doctors Hospital

🇺🇸

Columbus, Ohio, United States

Mount Carmel Grove City Hospital

🇺🇸

Grove City, Ohio, United States

Toledo Clinic Cancer Centers-Toledo

🇺🇸

Toledo, Ohio, United States

Saint Ann's Hospital

🇺🇸

Westerville, Ohio, United States

Saint Charles Health System

🇺🇸

Bend, Oregon, United States

Bay Area Hospital

🇺🇸

Coos Bay, Oregon, United States

Genesis Healthcare System Cancer Care Center

🇺🇸

Zanesville, Ohio, United States

American Fork Hospital / Huntsman Intermountain Cancer Center

🇺🇸

American Fork, Utah, United States

Clackamas Radiation Oncology Center

🇺🇸

Clackamas, Oregon, United States

Lewistown Hospital

🇺🇸

Lewistown, Pennsylvania, United States

Lehigh Valley Hospital-Cedar Crest

🇺🇸

Allentown, Pennsylvania, United States

Pocono Medical Center

🇺🇸

East Stroudsburg, Pennsylvania, United States

Community Medical Center

🇺🇸

Scranton, Pennsylvania, United States

Geisinger Medical Center

🇺🇸

Danville, Pennsylvania, United States

Saint Alphonsus Medical Center-Ontario

🇺🇸

Ontario, Oregon, United States

Prisma Health Cancer Institute - Spartanburg

🇺🇸

Boiling Springs, South Carolina, United States

Prisma Health Cancer Institute - Eastside

🇺🇸

Greenville, South Carolina, United States

MGC Hematology Oncology-Union

🇺🇸

Union, South Carolina, United States

Sandra L Maxwell Cancer Center

🇺🇸

Cedar City, Utah, United States

Jefferson Healthcare

🇺🇸

Port Townsend, Washington, United States

MultiCare Good Samaritan Hospital

🇺🇸

Puyallup, Washington, United States

Baptist Memorial Hospital and Cancer Center-Collierville

🇺🇸

Collierville, Tennessee, United States

MultiCare Tacoma General Hospital

🇺🇸

Tacoma, Washington, United States

MultiCare Deaconess Cancer and Blood Specialty Center - North

🇺🇸

Spokane, Washington, United States

Harrison HealthPartners Hematology and Oncology-Poulsbo

🇺🇸

Poulsbo, Washington, United States

Providence Regional Cancer System-Yelm

🇺🇸

Yelm, Washington, United States

Riverside Methodist Hospital

🇺🇸

Columbus, Ohio, United States

Mount Carmel Health Center West

🇺🇸

Columbus, Ohio, United States

Providence Regional Cancer System-Aberdeen

🇺🇸

Aberdeen, Washington, United States

Providence Saint Mary Regional Cancer Center

🇺🇸

Walla Walla, Washington, United States

Aurora Saint Luke's South Shore

🇺🇸

Cudahy, Wisconsin, United States

Aurora Health Care Germantown Health Center

🇺🇸

Germantown, Wisconsin, United States

Aurora BayCare Medical Center

🇺🇸

Green Bay, Wisconsin, United States

Froedtert and MCW Moorland Reserve Health Center

🇺🇸

New Berlin, Wisconsin, United States

Franciscan Research Center-Northwest Medical Plaza

🇺🇸

Tacoma, Washington, United States

MultiCare Deaconess Cancer and Blood Specialty Center - Downtown

🇺🇸

Spokane, Washington, United States

Aurora Cancer Care-Kenosha South

🇺🇸

Kenosha, Wisconsin, United States

PeaceHealth Saint John Medical Center

🇺🇸

Longview, Washington, United States

Valley Medical Center

🇺🇸

Renton, Washington, United States

North Star Lodge Cancer Center at Yakima Valley Memorial Hospital

🇺🇸

Yakima, Washington, United States

Aurora Cancer Care-Southern Lakes VLCC

🇺🇸

Burlington, Wisconsin, United States

Aurora Cancer Care-Milwaukee West

🇺🇸

Wauwatosa, Wisconsin, United States

Aurora Cancer Care-Racine

🇺🇸

Racine, Wisconsin, United States

PeaceHealth Southwest Medical Center

🇺🇸

Vancouver, Washington, United States

Mary Bridge Children's Hospital and Health Center

🇺🇸

Tacoma, Washington, United States

Northwest Medical Specialties PLLC

🇺🇸

Tacoma, Washington, United States

Aurora Bay Area Medical Group-Marinette

🇺🇸

Marinette, Wisconsin, United States

Cancer Center of Western Wisconsin

🇺🇸

New Richmond, Wisconsin, United States

Queen's Cancer Center - Pearlridge

🇺🇸

'Aiea, Hawaii, United States

Saint Alphonsus Cancer Care Center-Caldwell

🇺🇸

Caldwell, Idaho, United States

Kootenai Health - Coeur d'Alene

🇺🇸

Coeur d'Alene, Idaho, United States

Saint Luke's Cancer Institute - Meridian

🇺🇸

Meridian, Idaho, United States

Kootenai Cancer Clinic

🇺🇸

Sandpoint, Idaho, United States

Saint Luke's Cancer Institute - Twin Falls

🇺🇸

Twin Falls, Idaho, United States

Saint Anthony's Health

🇺🇸

Alton, Illinois, United States

Loyola Center for Health at Burr Ridge

🇺🇸

Burr Ridge, Illinois, United States

Rush - Copley Medical Center

🇺🇸

Aurora, Illinois, United States

Illinois CancerCare-Carthage

🇺🇸

Carthage, Illinois, United States

Illinois CancerCare-Canton

🇺🇸

Canton, Illinois, United States

Centralia Oncology Clinic

🇺🇸

Centralia, Illinois, United States

Carle on Vermilion

🇺🇸

Danville, Illinois, United States

Cancer Care Specialists of Illinois - Decatur

🇺🇸

Decatur, Illinois, United States

Decatur Memorial Hospital

🇺🇸

Decatur, Illinois, United States

Carle Physician Group-Effingham

🇺🇸

Effingham, Illinois, United States

Illinois CancerCare-Dixon

🇺🇸

Dixon, Illinois, United States

Crossroads Cancer Center

🇺🇸

Effingham, Illinois, United States

Illinois CancerCare-Eureka

🇺🇸

Eureka, Illinois, United States

Illinois CancerCare-Galesburg

🇺🇸

Galesburg, Illinois, United States

Western Illinois Cancer Treatment Center

🇺🇸

Galesburg, Illinois, United States

Illinois CancerCare-Kewanee Clinic

🇺🇸

Kewanee, Illinois, United States

Illinois CancerCare-Macomb

🇺🇸

Macomb, Illinois, United States

Carle Physician Group-Mattoon/Charleston

🇺🇸

Mattoon, Illinois, United States

Loyola University Medical Center

🇺🇸

Maywood, Illinois, United States

Marjorie Weinberg Cancer Center at Loyola-Gottlieb

🇺🇸

Melrose Park, Illinois, United States

Good Samaritan Regional Health Center

🇺🇸

Mount Vernon, Illinois, United States

Illinois CancerCare-Ottawa Clinic

🇺🇸

Ottawa, Illinois, United States

Illinois CancerCare-Pekin

🇺🇸

Pekin, Illinois, United States

Illinois CancerCare-Peoria

🇺🇸

Peoria, Illinois, United States

Methodist Medical Center of Illinois

🇺🇸

Peoria, Illinois, United States

Illinois CancerCare-Peru

🇺🇸

Peru, Illinois, United States

Valley Radiation Oncology

🇺🇸

Peru, Illinois, United States

Illinois CancerCare-Princeton

🇺🇸

Princeton, Illinois, United States

Southern Illinois University School of Medicine

🇺🇸

Springfield, Illinois, United States

Memorial Medical Center

🇺🇸

Springfield, Illinois, United States

Southwest Illinois Health Services LLP

🇺🇸

Swansea, Illinois, United States

Carle Cancer Center

🇺🇸

Urbana, Illinois, United States

The Carle Foundation Hospital

🇺🇸

Urbana, Illinois, United States

Illinois CancerCare - Washington

🇺🇸

Washington, Illinois, United States

Rush-Copley Healthcare Center

🇺🇸

Yorkville, Illinois, United States

Parkview Regional Medical Center

🇺🇸

Fort Wayne, Indiana, United States

McFarland Clinic PC - Ames

🇺🇸

Ames, Iowa, United States

Mary Greeley Medical Center

🇺🇸

Ames, Iowa, United States

McFarland Clinic PC-Boone

🇺🇸

Boone, Iowa, United States

Medical Oncology and Hematology Associates-West Des Moines

🇺🇸

Clive, Iowa, United States

Mercy Cancer Center-West Lakes

🇺🇸

Clive, Iowa, United States

Alegent Health Mercy Hospital

🇺🇸

Council Bluffs, Iowa, United States

Greater Regional Medical Center

🇺🇸

Creston, Iowa, United States

Prisma Health Cancer Institute - Easley

🇺🇸

Easley, South Carolina, United States

McFarland Clinic PC-Marshalltown

🇺🇸

Marshalltown, Iowa, United States

University of Iowa/Holden Comprehensive Cancer Center

🇺🇸

Iowa City, Iowa, United States

McFarland Clinic PC-Jefferson

🇺🇸

Jefferson, Iowa, United States

Mercy Medical Center-West Lakes

🇺🇸

West Des Moines, Iowa, United States

Kansas Institute of Medicine Cancer and Blood Center

🇺🇸

Lenexa, Kansas, United States

McFarland Clinic PC-Trinity Cancer Center

🇺🇸

Fort Dodge, Iowa, United States

Flaget Memorial Hospital

🇺🇸

Bardstown, Kentucky, United States

Commonwealth Cancer Center-Corbin

🇺🇸

Corbin, Kentucky, United States

Saint Joseph London

🇺🇸

London, Kentucky, United States

University of Maryland/Greenebaum Cancer Center

🇺🇸

Baltimore, Maryland, United States

Jewish Hospital Medical Center South

🇺🇸

Shepherdsville, Kentucky, United States

Hickman Cancer Center

🇺🇸

Adrian, Michigan, United States

Bronson Battle Creek

🇺🇸

Battle Creek, Michigan, United States

IHA Hematology Oncology Consultants-Brighton

🇺🇸

Brighton, Michigan, United States

Saint Joseph Mercy Brighton

🇺🇸

Brighton, Michigan, United States

IHA Hematology Oncology Consultants-Canton

🇺🇸

Canton, Michigan, United States

Saint Joseph Mercy Canton

🇺🇸

Canton, Michigan, United States

Caro Cancer Center

🇺🇸

Caro, Michigan, United States

IHA Hematology Oncology Consultants-Chelsea

🇺🇸

Chelsea, Michigan, United States

Hematology Oncology Consultants-Clarkston

🇺🇸

Clarkston, Michigan, United States

Saint Joseph Mercy Chelsea

🇺🇸

Chelsea, Michigan, United States

Newland Medical Associates-Clarkston

🇺🇸

Clarkston, Michigan, United States

Great Lakes Cancer Management Specialists-Doctors Park

🇺🇸

East China Township, Michigan, United States

Genesee Cancer and Blood Disease Treatment Center

🇺🇸

Flint, Michigan, United States

Genesee Hematology Oncology PC

🇺🇸

Flint, Michigan, United States

Hurley Medical Center

🇺🇸

Flint, Michigan, United States

Helen DeVos Children's Hospital at Spectrum Health

🇺🇸

Grand Rapids, Michigan, United States

Mercy Health Saint Mary's

🇺🇸

Grand Rapids, Michigan, United States

Spectrum Health at Butterworth Campus

🇺🇸

Grand Rapids, Michigan, United States

Great Lakes Cancer Management Specialists-Van Elslander Cancer Center

🇺🇸

Grosse Pointe Woods, Michigan, United States

Academic Hematology Oncology Specialists

🇺🇸

Grosse Pointe Woods, Michigan, United States

Michigan Breast Specialists-Grosse Pointe Woods

🇺🇸

Grosse Pointe Woods, Michigan, United States

Dixie Medical Center Regional Cancer Center

🇺🇸

Saint George, Utah, United States

Prisma Health Cancer Institute - Seneca

🇺🇸

Seneca, South Carolina, United States

Avera Cancer Institute

🇺🇸

Sioux Falls, South Dakota, United States

Sanford USD Medical Center - Sioux Falls

🇺🇸

Sioux Falls, South Dakota, United States

Memorial Hospital

🇺🇸

Chattanooga, Tennessee, United States

Baptist Memorial Hospital and Cancer Center-Memphis

🇺🇸

Memphis, Tennessee, United States

Memorial GYN Plus

🇺🇸

Ooltewah, Tennessee, United States

Saint Joseph Regional Cancer Center

🇺🇸

Bryan, Texas, United States

Logan Regional Hospital

🇺🇸

Logan, Utah, United States

Riverton Hospital

🇺🇸

Riverton, Utah, United States

MultiCare Auburn Medical Center

🇺🇸

Auburn, Washington, United States

Overlake Medical Center

🇺🇸

Bellevue, Washington, United States

PeaceHealth Saint Joseph Medical Center

🇺🇸

Bellingham, Washington, United States

Harrison Medical Center

🇺🇸

Bremerton, Washington, United States

Harrison HealthPartners Hematology and Oncology-Bremerton

🇺🇸

Bremerton, Washington, United States

Highline Medical Center-Main Campus

🇺🇸

Burien, Washington, United States

Swedish Cancer Institute-Edmonds

🇺🇸

Edmonds, Washington, United States

Providence Regional Cancer Partnership

🇺🇸

Everett, Washington, United States

Saint Elizabeth Hospital

🇺🇸

Enumclaw, Washington, United States

Saint Francis Hospital

🇺🇸

Federal Way, Washington, United States

Kadlec Clinic Hematology and Oncology

🇺🇸

Kennewick, Washington, United States

Swedish Cancer Institute-Issaquah

🇺🇸

Issaquah, Washington, United States

Saint Clare Hospital

🇺🇸

Lakewood, Washington, United States

MultiCare Deaconess Cancer and Blood Specialty Center - Valley

🇺🇸

Spokane Valley, Washington, United States

Aurora Health Center-Fond du Lac

🇺🇸

Fond Du Lac, Wisconsin, United States

Aurora Cancer Care-Grafton

🇺🇸

Grafton, Wisconsin, United States

Vince Lombardi Cancer Clinic - Oshkosh

🇺🇸

Oshkosh, Wisconsin, United States

Vince Lombardi Cancer Clinic-Sheboygan

🇺🇸

Sheboygan, Wisconsin, United States

Aurora West Allis Medical Center

🇺🇸

West Allis, Wisconsin, United States

Swedish Medical Center-First Hill

🇺🇸

Seattle, Washington, United States

University of Washington Medical Center - Montlake

🇺🇸

Seattle, Washington, United States

Pacific Gynecology Specialists

🇺🇸

Seattle, Washington, United States

Swedish Medical Center-Ballard Campus

🇺🇸

Seattle, Washington, United States

Fred Hutchinson Cancer Research Center

🇺🇸

Seattle, Washington, United States

Seattle Cancer Care Alliance

🇺🇸

Seattle, Washington, United States

Kaiser Permanente Washington

🇺🇸

Seattle, Washington, United States

Swedish Medical Center-Cherry Hill

🇺🇸

Seattle, Washington, United States

OptumCare Cancer Care at Charleston

🇺🇸

Las Vegas, Nevada, United States

University Medical Center of Southern Nevada

🇺🇸

Las Vegas, Nevada, United States

Cancer and Blood Specialists-Shadow

🇺🇸

Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway

🇺🇸

Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-San Martin

🇺🇸

Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada - Northwest

🇺🇸

Las Vegas, Nevada, United States

Las Vegas Urology - Smoke Ranch

🇺🇸

Las Vegas, Nevada, United States

Urology Specialists of Nevada - Southwest

🇺🇸

Las Vegas, Nevada, United States

Radiation Oncology Centers of Nevada Southeast

🇺🇸

Las Vegas, Nevada, United States

Ann M Wierman MD LTD

🇺🇸

Las Vegas, Nevada, United States

Cancer and Blood Specialists-Tenaya

🇺🇸

Las Vegas, Nevada, United States

GenesisCare USA - Vegas Tenaya

🇺🇸

Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-Tenaya

🇺🇸

Las Vegas, Nevada, United States

Las Vegas Urology - Cathedral Rock

🇺🇸

Las Vegas, Nevada, United States

OptumCare Cancer Care at MountainView

🇺🇸

Las Vegas, Nevada, United States

Urology Specialists of Nevada - Northwest

🇺🇸

Las Vegas, Nevada, United States

Alliance for Childhood Diseases/Cure 4 the Kids Foundation

🇺🇸

Las Vegas, Nevada, United States

Summerlin Hospital Medical Center

🇺🇸

Las Vegas, Nevada, United States

University Cancer Center

🇺🇸

Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada - Town Center

🇺🇸

Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada-Summerlin

🇺🇸

Las Vegas, Nevada, United States

Las Vegas Cancer Center-Medical Center

🇺🇸

Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada

🇺🇸

Las Vegas, Nevada, United States

GenesisCare USA - Fort Apache

🇺🇸

Las Vegas, Nevada, United States

OptumCare Cancer Care at Fort Apache

🇺🇸

Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills

🇺🇸

Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada - Central Valley

🇺🇸

Las Vegas, Nevada, United States

University of Cincinnati Cancer Center-UC Medical Center

🇺🇸

Cincinnati, Ohio, United States

Good Samaritan Hospital - Cincinnati

🇺🇸

Cincinnati, Ohio, United States

Bethesda North Hospital

🇺🇸

Cincinnati, Ohio, United States

TriHealth Cancer Institute-Westside

🇺🇸

Cincinnati, Ohio, United States

TriHealth Cancer Institute-Anderson

🇺🇸

Cincinnati, Ohio, United States

Duke University Medical Center

🇺🇸

Durham, North Carolina, United States

Abbott-Northwestern Hospital

🇺🇸

Minneapolis, Minnesota, United States

Hennepin County Medical Center

🇺🇸

Minneapolis, Minnesota, United States

Health Partners Inc

🇺🇸

Minneapolis, Minnesota, United States

Huntsman Cancer Institute/University of Utah

🇺🇸

Salt Lake City, Utah, United States

LDS Hospital

🇺🇸

Salt Lake City, Utah, United States

George E Wahlen Department of Veterans Affairs Medical Center

🇺🇸

Salt Lake City, Utah, United States

Hawaii Cancer Care - Savio

🇺🇸

'Aiea, Hawaii, United States

Wilcox Memorial Hospital and Kauai Medical Clinic

🇺🇸

Lihue, Hawaii, United States

Wesley Medical Center

🇺🇸

Wichita, Kansas, United States

Island Urology-Hilo

🇺🇸

Hilo, Hawaii, United States

Menorah Medical Center

🇺🇸

Overland Park, Kansas, United States

Cancer Center of Kansas - Wichita

🇺🇸

Wichita, Kansas, United States

Sanford Medical Center Fargo

🇺🇸

Fargo, North Dakota, United States

Pali Momi Medical Center

🇺🇸

'Aiea, Hawaii, United States

Sanford Broadway Medical Center

🇺🇸

Fargo, North Dakota, United States

Lawrence Memorial Hospital

🇺🇸

Lawrence, Kansas, United States

The Cancer Center of Hawaii-Pali Momi

🇺🇸

'Aiea, Hawaii, United States

Sanford Roger Maris Cancer Center

🇺🇸

Fargo, North Dakota, United States

Central Care Cancer Center - Garden City

🇺🇸

Garden City, Kansas, United States

Cancer Center of Kansas-Wichita Medical Arts Tower

🇺🇸

Wichita, Kansas, United States

Ascension Via Christi Hospitals Wichita

🇺🇸

Wichita, Kansas, United States

Minimally Invasive Surgery Hospital

🇺🇸

Lenexa, Kansas, United States

Central Care Cancer Center - Great Bend

🇺🇸

Great Bend, Kansas, United States

Billings Clinic-Cody

🇺🇸

Cody, Wyoming, United States

Cheyenne Regional Medical Center-West

🇺🇸

Cheyenne, Wyoming, United States

Welch Cancer Center

🇺🇸

Sheridan, Wyoming, United States

Cancer Center at Saint Joseph's

🇺🇸

Phoenix, Arizona, United States

Ascension Saint John Hospital

🇺🇸

Detroit, Michigan, United States

University of Oklahoma Health Sciences Center

🇺🇸

Oklahoma City, Oklahoma, United States

Mercy Hospital Oklahoma City

🇺🇸

Oklahoma City, Oklahoma, United States

Fairbanks Memorial Hospital

🇺🇸

Fairbanks, Alaska, United States

Saint Luke's Cancer Institute - Nampa

🇺🇸

Nampa, Idaho, United States

Saint Luke's Cancer Institute - Fruitland

🇺🇸

Fruitland, Idaho, United States

Alaska Women's Cancer Care

🇺🇸

Anchorage, Alaska, United States

Kingman Regional Medical Center

🇺🇸

Kingman, Arizona, United States

Saint Luke's Cancer Institute - Boise

🇺🇸

Boise, Idaho, United States

Saint Alphonsus Medical Center-Nampa

🇺🇸

Nampa, Idaho, United States

Saint Alphonsus Cancer Care Center-Boise

🇺🇸

Boise, Idaho, United States

Idaho Urologic Institute-Meridian

🇺🇸

Meridian, Idaho, United States

Saint Vincent Frontier Cancer Center

🇺🇸

Billings, Montana, United States

Kootenai Clinic Cancer Services - Post Falls

🇺🇸

Post Falls, Idaho, United States

Baptist Cancer Center-Grenada

🇺🇸

Grenada, Mississippi, United States

Baptist Memorial Hospital and Cancer Center-Union County

🇺🇸

New Albany, Mississippi, United States

Community Hospital of Anaconda

🇺🇸

Anaconda, Montana, United States

Hope Cancer Care of Nevada

🇺🇸

Las Vegas, Nevada, United States

Urology Specialists of Nevada - Central

🇺🇸

Las Vegas, Nevada, United States

Saint Patrick Hospital - Community Hospital

🇺🇸

Missoula, Montana, United States

Bozeman Deaconess Hospital

🇺🇸

Bozeman, Montana, United States

Baptist Memorial Hospital and Cancer Center-Desoto

🇺🇸

Southhaven, Mississippi, United States

Community Medical Hospital

🇺🇸

Missoula, Montana, United States

Las Vegas Cancer Center-Henderson

🇺🇸

Henderson, Nevada, United States

Benefis Healthcare- Sletten Cancer Institute

🇺🇸

Great Falls, Montana, United States

Saint Vincent Healthcare

🇺🇸

Billings, Montana, United States

Walter Knox Memorial Hospital

🇺🇸

Emmett, Idaho, United States

Saint Peter's Community Hospital

🇺🇸

Helena, Montana, United States

GenesisCare USA - Las Vegas

🇺🇸

Las Vegas, Nevada, United States

Saint James Community Hospital and Cancer Treatment Center

🇺🇸

Butte, Montana, United States

Prisma Health Cancer Institute - Butternut

🇺🇸

Greenville, South Carolina, United States

Prisma Health Cancer Institute - Faris

🇺🇸

Greenville, South Carolina, United States

Las Vegas Prostate Cancer Center

🇺🇸

Las Vegas, Nevada, United States

Midlands Community Hospital

🇺🇸

Papillion, Nebraska, United States

Mercy Hospital Springfield

🇺🇸

Springfield, Missouri, United States

Great Falls Clinic

🇺🇸

Great Falls, Montana, United States

Carson Tahoe Regional Medical Center

🇺🇸

Carson City, Nevada, United States

Las Vegas Urology - Pecos

🇺🇸

Las Vegas, Nevada, United States

Desert West Surgery

🇺🇸

Las Vegas, Nevada, United States

OptumCare Cancer Care at Seven Hills

🇺🇸

Henderson, Nevada, United States

Cancer and Blood Specialists-Henderson

🇺🇸

Henderson, Nevada, United States

Radiation Oncology Centers of Nevada Central

🇺🇸

Las Vegas, Nevada, United States

Billings Clinic Cancer Center

🇺🇸

Billings, Montana, United States

CHI Health Saint Francis

🇺🇸

Grand Island, Nebraska, United States

Gibbs Cancer Center-Gaffney

🇺🇸

Gaffney, South Carolina, United States

Pulmonary Medicine Center of Chattanooga-Hixson

🇺🇸

Hixson, Tennessee, United States

Radiation Oncology Associates

🇺🇸

Reno, Nevada, United States

Prisma Health Cancer Institute - Greer

🇺🇸

Greer, South Carolina, United States

Heartland Hematology and Oncology

🇺🇸

Kearney, Nebraska, United States

Saint Mary's Regional Medical Center

🇺🇸

Reno, Nevada, United States

Las Vegas Urology - Sunset

🇺🇸

Las Vegas, Nevada, United States

Cancer Therapy and Integrative Medicine

🇺🇸

Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada-Horizon Ridge

🇺🇸

Henderson, Nevada, United States

Renown Regional Medical Center

🇺🇸

Reno, Nevada, United States

Sunrise Hospital and Medical Center

🇺🇸

Las Vegas, Nevada, United States

Hope Cancer Care of Nevada-Pahrump

🇺🇸

Pahrump, Nevada, United States

Gibbs Cancer Center-Pelham

🇺🇸

Greer, South Carolina, United States

Spartanburg Medical Center

🇺🇸

Spartanburg, South Carolina, United States

Sanford Cancer Center Oncology Clinic

🇺🇸

Sioux Falls, South Dakota, United States

Cancer Center of Colorado at Sloan's Lake

🇺🇸

Denver, Colorado, United States

Denver Health Medical Center

🇺🇸

Denver, Colorado, United States

National Jewish Health-Main Campus

🇺🇸

Denver, Colorado, United States

The Women's Imaging Center

🇺🇸

Denver, Colorado, United States

Porter Adventist Hospital

🇺🇸

Denver, Colorado, United States

Rocky Mountain Cancer Centers-Midtown

🇺🇸

Denver, Colorado, United States

SCL Health Saint Joseph Hospital

🇺🇸

Denver, Colorado, United States

Rocky Mountain Cancer Centers-Rose

🇺🇸

Denver, Colorado, United States

Rose Medical Center

🇺🇸

Denver, Colorado, United States

Western Surgical Care

🇺🇸

Denver, Colorado, United States

Providence Portland Medical Center

🇺🇸

Portland, Oregon, United States

Oregon Health and Science University

🇺🇸

Portland, Oregon, United States

Aurora Saint Luke's Medical Center

🇺🇸

Milwaukee, Wisconsin, United States

Aurora Sinai Medical Center

🇺🇸

Milwaukee, Wisconsin, United States

Nebraska Cancer Specialists/Oncology Hematology West PC - MECC

🇺🇸

Omaha, Nebraska, United States

Nebraska Methodist Hospital

🇺🇸

Omaha, Nebraska, United States

Oncology Associates PC

🇺🇸

Omaha, Nebraska, United States

Alegent Health Immanuel Medical Center

🇺🇸

Omaha, Nebraska, United States

Hematology and Oncology Consultants PC

🇺🇸

Omaha, Nebraska, United States

Aurora Cancer Care-Milwaukee

🇺🇸

Milwaukee, Wisconsin, United States

Alegent Health Bergan Mercy Medical Center

🇺🇸

Omaha, Nebraska, United States

Creighton University Medical Center

🇺🇸

Omaha, Nebraska, United States

Medical College of Wisconsin

🇺🇸

Milwaukee, Wisconsin, United States

Alegent Health Lakeside Hospital

🇺🇸

Omaha, Nebraska, United States

Parkland Health Center - Farmington

🇺🇸

Farmington, Missouri, United States

Delbert Day Cancer Institute at PCRMC

🇺🇸

Rolla, Missouri, United States

Heartland Regional Medical Center

🇺🇸

Saint Joseph, Missouri, United States

Freeman Health System

🇺🇸

Joplin, Missouri, United States

Mercy Hospital Joplin

🇺🇸

Joplin, Missouri, United States

CoxHealth South Hospital

🇺🇸

Springfield, Missouri, United States

Saint Louis Cancer and Breast Institute-South City

🇺🇸

Saint Louis, Missouri, United States

Mercy Hospital Washington

🇺🇸

Washington, Missouri, United States

Mercy Hospital Saint Louis

🇺🇸

Saint Louis, Missouri, United States

Utah Cancer Specialists-Salt Lake City

🇺🇸

Salt Lake City, Utah, United States

Intermountain Medical Center

🇺🇸

Murray, Utah, United States

McKay-Dee Hospital Center

🇺🇸

Ogden, Utah, United States

Utah Valley Regional Medical Center

🇺🇸

Provo, Utah, United States

New Ulm Medical Center

🇺🇸

New Ulm, Minnesota, United States

Fairview Northland Medical Center

🇺🇸

Princeton, Minnesota, United States

Saint Francis Regional Medical Center

🇺🇸

Shakopee, Minnesota, United States

Ridgeview Medical Center

🇺🇸

Waconia, Minnesota, United States

Minnesota Oncology Hematology PA-Woodbury

🇺🇸

Woodbury, Minnesota, United States

Sanford Cancer Center Worthington

🇺🇸

Worthington, Minnesota, United States

Colorado Blood Cancer Institute

🇺🇸

Denver, Colorado, United States

Presbyterian - Saint Lukes Medical Center - Health One

🇺🇸

Denver, Colorado, United States

Hope Cancer Clinic

🇺🇸

Livonia, Michigan, United States

Borgess Medical Center

🇺🇸

Kalamazoo, Michigan, United States

Saint Joseph Mercy Oakland

🇺🇸

Pontiac, Michigan, United States

Saint Mary Mercy Hospital

🇺🇸

Livonia, Michigan, United States

Mercy Health Mercy Campus

🇺🇸

Muskegon, Michigan, United States

Huron Medical Center PC

🇺🇸

Port Huron, Michigan, United States

Spectrum Health Reed City Hospital

🇺🇸

Reed City, Michigan, United States

Michigan Breast Specialists-Macomb Township

🇺🇸

Macomb, Michigan, United States

Ascension Saint Mary's Hospital

🇺🇸

Saginaw, Michigan, United States

Oncology Hematology Associates of Saginaw Valley PC

🇺🇸

Saginaw, Michigan, United States

Marie Yeager Cancer Center

🇺🇸

Saint Joseph, Michigan, United States

Bhadresh Nayak MD PC-Sterling Heights

🇺🇸

Sterling Heights, Michigan, United States

Munson Medical Center

🇺🇸

Traverse City, Michigan, United States

Advanced Breast Care Center PLLC

🇺🇸

Warren, Michigan, United States

Macomb Hematology Oncology PC

🇺🇸

Warren, Michigan, United States

Ascension Saint Joseph Hospital

🇺🇸

Tawas City, Michigan, United States

IHA Hematology Oncology Consultants-Ann Arbor

🇺🇸

Ypsilanti, Michigan, United States

Saint Mary's Oncology/Hematology Associates of West Branch

🇺🇸

West Branch, Michigan, United States

Metro Health Hospital

🇺🇸

Wyoming, Michigan, United States

Columbus Oncology and Hematology Associates Inc

🇺🇸

Columbus, Ohio, United States

Delaware Radiation Oncology

🇺🇸

Delaware, Ohio, United States

Grady Memorial Hospital

🇺🇸

Delaware, Ohio, United States

Marietta Memorial Hospital

🇺🇸

Marietta, Ohio, United States

Dublin Methodist Hospital

🇺🇸

Dublin, Ohio, United States

Toledo Radiation Oncology at Northwest Ohio Onocolgy Center

🇺🇸

Maumee, Ohio, United States

OhioHealth Marion General Hospital

🇺🇸

Marion, Ohio, United States

Knox Community Hospital

🇺🇸

Mount Vernon, Ohio, United States

Newark Radiation Oncology

🇺🇸

Newark, Ohio, United States

Saint Vincent Mercy Medical Center

🇺🇸

Toledo, Ohio, United States

Providence Cancer Institute Clackamas Clinic

🇺🇸

Clackamas, Oregon, United States

Mercy Health Perrysburg Cancer Center

🇺🇸

Perrysburg, Ohio, United States

University of Cincinnati Cancer Center-West Chester

🇺🇸

West Chester, Ohio, United States

Lehigh Valley Hospital - Muhlenberg

🇺🇸

Bethlehem, Pennsylvania, United States

Providence Newberg Medical Center

🇺🇸

Newberg, Oregon, United States

Saint Charles Health System-Redmond

🇺🇸

Redmond, Oregon, United States

Geisinger Medical Center-Cancer Center Hazleton

🇺🇸

Hazleton, Pennsylvania, United States

Providence Saint Vincent Medical Center

🇺🇸

Portland, Oregon, United States

Lehigh Valley Hospital-Hazleton

🇺🇸

Hazleton, Pennsylvania, United States

Geisinger Medical Oncology-Lewisburg

🇺🇸

Lewisburg, Pennsylvania, United States

Geisinger Medical Group

🇺🇸

State College, Pennsylvania, United States

PeaceHealth United General Medical Center

🇺🇸

Sedro-Woolley, Washington, United States

Vince Lombardi Cancer Clinic-Two Rivers

🇺🇸

Two Rivers, Wisconsin, United States

Sanford Bismarck Medical Center

🇺🇸

Bismarck, North Dakota, United States

Geisinger Medical Oncology-Selinsgrove

🇺🇸

Selinsgrove, Pennsylvania, United States

Fairfield Medical Center

🇺🇸

Lancaster, Ohio, United States

Mercy Health - Saint Anne Hospital

🇺🇸

Toledo, Ohio, United States

OhioHealth Mansfield Hospital

🇺🇸

Mansfield, Ohio, United States

Geisinger Cancer Services-Pottsville

🇺🇸

Pottsville, Pennsylvania, United States

Providence Regional Cancer System-Shelton

🇺🇸

Shelton, Washington, United States

Aurora Medical Center in Summit

🇺🇸

Summit, Wisconsin, United States

The Mark H Zangmeister Center

🇺🇸

Columbus, Ohio, United States

Mountain Blue Cancer Care Center - Swedish

🇺🇸

Englewood, Colorado, United States

Rocky Mountain Cancer Centers-Aurora

🇺🇸

Aurora, Colorado, United States

The Medical Center of Aurora

🇺🇸

Aurora, Colorado, United States

Moffitt Cancer Center-International Plaza

🇺🇸

Tampa, Florida, United States

Moffitt Cancer Center - McKinley Campus

🇺🇸

Tampa, Florida, United States

Moffitt Cancer Center

🇺🇸

Tampa, Florida, United States

Saint Joseph Mercy Hospital

🇺🇸

Ann Arbor, Michigan, United States

North Memorial Medical Health Center

🇺🇸

Robbinsdale, Minnesota, United States

Geisinger Wyoming Valley/Henry Cancer Center

🇺🇸

Wilkes-Barre, Pennsylvania, United States

Rice Memorial Hospital

🇺🇸

Willmar, Minnesota, United States

Mercy Clinic-Rolla-Cancer and Hematology

🇺🇸

Rolla, Missouri, United States

Michigan Breast Specialists-Warren

🇺🇸

Warren, Michigan, United States

Missouri Baptist Medical Center

🇺🇸

Saint Louis, Missouri, United States

Las Vegas Urology - Green Valley

🇺🇸

Henderson, Nevada, United States

Las Vegas Urology - Pebble

🇺🇸

Henderson, Nevada, United States

Saint Elizabeth Regional Medical Center

🇺🇸

Lincoln, Nebraska, United States

Comprehensive Cancer Centers of Nevada - Henderson

🇺🇸

Henderson, Nevada, United States

Comprehensive Cancer Centers of Nevada-Southeast Henderson

🇺🇸

Henderson, Nevada, United States

GenesisCare USA - Henderson

🇺🇸

Henderson, Nevada, United States

Urology Specialists of Nevada - Green Valley

🇺🇸

Henderson, Nevada, United States

Saints Mary and Elizabeth Hospital

🇺🇸

Louisville, Kentucky, United States

UofL Health Medical Center Northeast

🇺🇸

Louisville, Kentucky, United States

Jewish Hospital

🇺🇸

Louisville, Kentucky, United States

Research Medical Center

🇺🇸

Kansas City, Missouri, United States

Hawaii Cancer Care Inc - Waterfront Plaza

🇺🇸

Honolulu, Hawaii, United States

Island Urology

🇺🇸

Honolulu, Hawaii, United States

Queen's Cancer Cenrer - POB I

🇺🇸

Honolulu, Hawaii, United States

Queen's Medical Center

🇺🇸

Honolulu, Hawaii, United States

Straub Clinic and Hospital

🇺🇸

Honolulu, Hawaii, United States

University of Hawaii Cancer Center

🇺🇸

Honolulu, Hawaii, United States

Hawaii Cancer Care Inc-Liliha

🇺🇸

Honolulu, Hawaii, United States

Kuakini Medical Center

🇺🇸

Honolulu, Hawaii, United States

Queen's Cancer Center - Kuakini

🇺🇸

Honolulu, Hawaii, United States

The Cancer Center of Hawaii-Liliha

🇺🇸

Honolulu, Hawaii, United States

Kapiolani Medical Center for Women and Children

🇺🇸

Honolulu, Hawaii, United States

Medical Oncology and Hematology Associates-Laurel

🇺🇸

Des Moines, Iowa, United States

Mercy Medical Center - Des Moines

🇺🇸

Des Moines, Iowa, United States

Saint Joseph Radiation Oncology Resource Center

🇺🇸

Lexington, Kentucky, United States

Saint Joseph Hospital East

🇺🇸

Lexington, Kentucky, United States

University of Rochester

🇺🇸

Rochester, New York, United States

21st Century Oncology-Pontiac

🇺🇸

Pontiac, Michigan, United States

Saint Francis Medical Center

🇺🇸

Cape Girardeau, Missouri, United States

Illinois CancerCare-Bloomington

🇺🇸

Bloomington, Illinois, United States

Loyola Medicine Homer Glen

🇺🇸

Homer Glen, Illinois, United States

Toledo Clinic Cancer Centers-Monroe

🇺🇸

Monroe, Michigan, United States

Lake Huron Medical Center

🇺🇸

Port Huron, Michigan, United States

Great Lakes Cancer Management Specialists-Rochester Hills

🇺🇸

Rochester Hills, Michigan, United States

Sanford Joe Lueken Cancer Center

🇺🇸

Bemidji, Minnesota, United States

Sanford Thief River Falls Medical Center

🇺🇸

Thief River Falls, Minnesota, United States

Fairview Lakes Medical Center

🇺🇸

Wyoming, Minnesota, United States

Centerpoint Medical Center LLC

🇺🇸

Independence, Missouri, United States

Capital Region Southwest Campus

🇺🇸

Jefferson City, Missouri, United States

Southern Ohio Medical Center

🇺🇸

Portsmouth, Ohio, United States

Saint Alphonsus Medical Center-Baker City

🇺🇸

Baker City, Oregon, United States

Providence Regional Cancer System-Centralia

🇺🇸

Centralia, Washington, United States

MultiCare Gig Harbor Medical Park

🇺🇸

Gig Harbor, Washington, United States

Providence Regional Cancer System-Lacey

🇺🇸

Lacey, Washington, United States

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