Influence of deep brain stimulation of the nucleus subthalamicus on motor adaptation in subjects with Parkinson's disease
Not Applicable
Recruiting
- Conditions
- G20.1
- Registration Number
- DRKS00031514
- Lead Sponsor
- niversitätsklinikum Leipzig, Neurologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Specific to individuals with Parkinson's disease: Hoehn and Yahr stages 2 to 4 and condition after implantation of a deep brain stimulation system of STN and current therapy hereby
Exclusion Criteria
Alcohol/drug abuse (current or history). Other neurological disease with the exception of idiopathic Parkinson's syndrome. Depression ( BDI>19 points). Severe previous internal disease (e.g., heart failure) or orthopedic/rheumatologic disease. Inability to perform the experimental tasks. Pregnancy as per self-report. Relevant cognitive impairment (MOCA score < 18)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Angular error during the two adaptation conditions as well as in the de-adaptation condition. The angular error is defined as the difference between a straight line connecting the center cross to the target and a line connecting the center cross to the position of the cursor at maximum speed.
- Secondary Outcome Measures
Name Time Method Reaction times and the movement times.