Influence of deep brain stimulation of the subthalamic nucleus on motor sequence learning in people with Parkinson's disease
- Conditions
- G20.1
- Registration Number
- DRKS00022297
- Lead Sponsor
- Klinik für Neurologie, Uniklinik Leipzig
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Persons aged 30 to 75 years;
- Specific to persons with Parkinson's disease: condition following implantation of a system for deep brain stimulation of the subthalamic nucleus and current therapy
- Specific for people with Parkinson's disease: Hoehn and Yahr stages 1 to 4
- Right handed
- Signing of the declaration of consent
- Non-consent or inability of the subject to consent to participate in the study
- Alcohol/drug abuse (current or previous history)
- other neurological diseases with the exception of idiopathic Parkinson's syndrome
- Depression (BDI > 19 points)
- acute psychotic symptoms
- serious pre-existing medical conditions (e.g. heart failure) or pre-existing orthopaedic/rheumatological conditions that interfere with the execution of the expenditure
- inability to perform the experimental tasks
- Pregnancy according to self-disclosure
- relevant cognitive impairment (MOCA score < 26)
- relevant daytime fatigue (ESS >12)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Ability of motor learning or the consolidation of what has been learned in THS mode on or off
- Secondary Outcome Measures
Name Time Method Influence of the stimulation site of THS in the STN on motor learning or consolidation