Mifepristone as a single agent versus mifepristone followed by misoprostol for second trimester termination of pregnancy in women with previous caesarean

Diksha Malhotra0 个研究点目标入组 0 人开始时间: 待定最近更新: 2023年6月26日

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•All women with previous caesarean section requiring termination of pregnancy between 14-24 weeks
•1) 18 years or older
•2) Singleton gestation
•3) Late miscarriage/inevitable abortion between 14-20 weeks
•4) Pregnancy getting terminated for lethal fetal anomalies/medical or social reasons between 14-24 weeks(under MTP Amendment Act,2021)
•5) Intra uterine fetal death (IUFD)/previable premature rupture of membranes(PPROM)between 20-24 weeks

•1) Known contraindication to mifepristone(chronic adrenal failure, long term steroid treatment,concurrent anticoagulation therapy,bleeding disorders,inherited porphyrias)
•2) Known contraindication to misoprostol(renal impairment,inflammatory bowel disease, pre existing heart disease,unexplained vaginal bleeding,known allergies)
•3) Previous myomectomy or nature of scar unknown or previous history of uterine rupture
•4) Severe anaemia
•5) Evidence of sepsis

发起方

Diksha Malhotra