To observe and compare the effect of injection of a drug ( medicine) at two different sites in between muscles for pain relief in patients who undergo breast cancer surgery.
Not Applicable
Completed
- Conditions
- Health Condition 1: C509- Malignant neoplasm of breast of unspecified site
- Registration Number
- CTRI/2019/03/018067
- Lead Sponsor
- Department of Anaesthesia and Intensive care
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
1.Females suffering from carcinoma breast.
2.American Society of Anaesthesiologists status I-II
3.Age ranging from 18-80 years
Exclusion Criteria
1.Patient refusal.
2.History of relevant drug allergy.
3.History of psychiatric illness and substance abuse.
4.Patient suffering from severe cardiovascular, respiratory,liver, metabolic or neurological disease.
5.Chronic treatment with analgesics.
6.Pregnant patient.
7.Coagulopathy.
8.Infection at planned injection site.
9.Psychological inability of the patient to understand and interpret visual analogue scale.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the reduction in pain intensity in post-operative period by using linear visual analogue scale (VAS) score in patients receiving either ESP block or SAM block following MRM.Timepoint: Post-operative at 30 mins,1 hr,4 hrs,8 hrs,12 hrs and 24 hrs.
- Secondary Outcome Measures
Name Time Method 1.Morphine consumption over 24 hrs <br/ ><br>2.Total dose of antiemetics over 24 hours. <br/ ><br>3.Safety profile of both the blocks. <br/ ><br>4.Changes in hemodynamic variables. <br/ ><br>5.Side effects pertaining to the procedure or drugs.Timepoint: 1.Post-operative at 30 mins,1 hr,4 hrs,8 hrs,12 hrs and 24 hrs. <br/ ><br>2.Post-operative at 30 mins,1 hr,4 hrs,8 hrs,12 hrs and 24 hrs. <br/ ><br>3.Post-operative at 30 mins,1 hr,4 hrs,8 hrs,12 hrs and 24 hrs. <br/ ><br>4.Post-operative at 30 mins,1 hr,4 hrs,8 hrs,12 hrs and 24 hrs. <br/ ><br>5.Post-operative at 30 mins,1 hr,4 hrs,8 hrs,12 hrs and 24 hrs.