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临床试验/NCT04539054
NCT04539054已完成不适用

Effects of a Multi-ingredient Pre-workout Supplement Versus Caffeine on Energy Expenditure and Feelings of Fatigue During Low-intensity Treadmill Exercise in College-aged Males.

Northern Illinois University2 个研究点 分布在 1 个国家目标入组 12 人开始时间: 2019年9月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
12
试验地点
2
主要终点
Energy expenditure

研究概览

简要总结

The primary purpose of this study was to examine the acute effects of a multi-ingredient pre-workout supplement versus an ergogenic dose of caffeine (6 mg/kg) on energy expenditure during low-intensity exercise. The effects of these substances on substrate utilization, gas exchange, and psychological factors were also investigated. Twelve males (mean ± SD: age = 22.8 ± 2.4 years) completed three bouts of 60-min of treadmill exercise at 4.8-6.4 km/hr on separate days after consuming a pre-workout supplement, 6 mg/kg of caffeine, or placebo in a randomized fashion. The pre-workout and caffeine supplements resulted in significantly greater energy expenditure (p < 0.001, p = 0.006, respectively), VO2 (p < 0.001, p = 0.007, respectively), VCO2 (p = 0.006, p = 0.049, respectively), and VE (p < 0.001, p = 0.007, respectively), but not rates of fat or carbohydrate oxidation or respiratory exchange ratio compared to placebo (collapsed across condition). In addition, the pre-workout supplement increased feelings of alertness (p = 0.015) and focus (p = 0.005) 30-minutes post-ingestion and decreased feelings of fatigue (p = 0.014) during exercise compared to placebo (collapsed across condition). Thus, the pre-workout supplement increased energy expenditure and measures of gas exchange to the same extent as 6 mg/kg of caffeine with concomitant increased feelings of alertness and focus and decreased feelings of fatigue.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Treatment
盲法
Double (Participant, Investigator)

入排标准

年龄范围
19 Years 至 29 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • 未提供

排除标准

  • history of medical or surgical events, including cardiovascular disease, metabolic, renal, hepatic, or musculoskeletal disorders;
  • use of any medications
  • use of nutritional supplements
  • habitual use of caffeine (≥1 caffeinated beverage per day)
  • participation in another clinical trial or investigation of another investigational product within 30 days prior to screening/enrollment.

结局指标

主要结局

Energy expenditure

时间窗: Measured continuously during 60 minutes of exercise for all three supplement conditions

Measurement of caloric expenditure via gas exchange

次要结局

  • Oxygen consumption(Measured continuously during 60 minutes of exercise for all three supplement conditions)
  • Minute ventilation(Measured continuously during 60 minutes of exercise for all three supplement conditions)
  • Rate of carbohydrate oxidation(Measured continuously during 60 minutes of exercise for all three supplement conditions)
  • Feelings of focus(Baseline, 30-minutes post-ingestion of supplement, and at the 30-minute time point of exercise for all three supplement conditions)
  • Rate of fat oxidation(Measured continuously during 60 minutes of exercise for all three supplement conditions)
  • Carbon dioxide production(Measured continuously during 60 minutes of exercise for all three supplement conditions)
  • Feelings of fatigue(Baseline, 30-minutes post-ingestion of supplement, and at the 30-minute time point of exercise for all three supplement conditions)
  • Feelings of energy(Baseline, 30-minutes post-ingestion of supplement, and at the 30-minute time point of exercise for all three supplement conditions)
  • Feelings of alertness(Baseline, 30-minutes post-ingestion of supplement, and at the 30-minute time point of exercise for all three supplement conditions)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Clayton Camic

Associate Professor

Northern Illinois University

研究点 (2)

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