Effects of a Multi-ingredient Pre-workout Supplement Versus Caffeine on Energy Expenditure and Feelings of Fatigue During Low-intensity Treadmill Exercise in College-aged Males.
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Northern Illinois University
- Enrollment
- 12
- Locations
- 1
- Primary Endpoint
- Energy expenditure
Study Overview
Brief Summary
The primary purpose of this study was to examine the acute effects of a multi-ingredient pre-workout supplement versus an ergogenic dose of caffeine (6 mg/kg) on energy expenditure during low-intensity exercise. The effects of these substances on substrate utilization, gas exchange, and psychological factors were also investigated. Twelve males (mean ± SD: age = 22.8 ± 2.4 years) completed three bouts of 60-min of treadmill exercise at 4.8-6.4 km/hr on separate days after consuming a pre-workout supplement, 6 mg/kg of caffeine, or placebo in a randomized fashion. The pre-workout and caffeine supplements resulted in significantly greater energy expenditure (p < 0.001, p = 0.006, respectively), VO2 (p < 0.001, p = 0.007, respectively), VCO2 (p = 0.006, p = 0.049, respectively), and VE (p < 0.001, p = 0.007, respectively), but not rates of fat or carbohydrate oxidation or respiratory exchange ratio compared to placebo (collapsed across condition). In addition, the pre-workout supplement increased feelings of alertness (p = 0.015) and focus (p = 0.005) 30-minutes post-ingestion and decreased feelings of fatigue (p = 0.014) during exercise compared to placebo (collapsed across condition). Thus, the pre-workout supplement increased energy expenditure and measures of gas exchange to the same extent as 6 mg/kg of caffeine with concomitant increased feelings of alertness and focus and decreased feelings of fatigue.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Treatment
- Masking
- Double (Participant, Investigator)
Eligibility Criteria
- Ages
- 19 Years to 29 Years (Adult)
- Sex
- Male
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- Not provided
Exclusion Criteria
- •history of medical or surgical events, including cardiovascular disease, metabolic, renal, hepatic, or musculoskeletal disorders;
- •use of any medications
- •use of nutritional supplements
- •habitual use of caffeine (≥1 caffeinated beverage per day)
- •participation in another clinical trial or investigation of another investigational product within 30 days prior to screening/enrollment.
Arms & Interventions
Pre-Workout Condition
This condition consisted of the ingestion of one serving of the pre-workout supplement.
Intervention: ENGN Shred (Dietary Supplement)
Caffeine Condition
This condition consisted of the ingestion of 6 mg of caffeine per kg of body mass.
Intervention: Nutricost caffeine powder (Dietary Supplement)
Placebo condition
This condition consisted of the ingestion of a placebo.
Intervention: Crystal Light (Dietary Supplement)
Outcomes
Primary Outcomes
Energy expenditure
Time Frame: Measured continuously during 60 minutes of exercise for all three supplement conditions
Measurement of caloric expenditure via gas exchange
Secondary Outcomes
- Oxygen consumption(Measured continuously during 60 minutes of exercise for all three supplement conditions)
- Minute ventilation(Measured continuously during 60 minutes of exercise for all three supplement conditions)
- Rate of carbohydrate oxidation(Measured continuously during 60 minutes of exercise for all three supplement conditions)
- Feelings of focus(Baseline, 30-minutes post-ingestion of supplement, and at the 30-minute time point of exercise for all three supplement conditions)
- Rate of fat oxidation(Measured continuously during 60 minutes of exercise for all three supplement conditions)
- Carbon dioxide production(Measured continuously during 60 minutes of exercise for all three supplement conditions)
- Feelings of fatigue(Baseline, 30-minutes post-ingestion of supplement, and at the 30-minute time point of exercise for all three supplement conditions)
- Feelings of energy(Baseline, 30-minutes post-ingestion of supplement, and at the 30-minute time point of exercise for all three supplement conditions)
- Feelings of alertness(Baseline, 30-minutes post-ingestion of supplement, and at the 30-minute time point of exercise for all three supplement conditions)
Investigators
Clayton Camic
Associate Professor
Northern Illinois University