Effects of a Pre-Workout Dietary Supplement on Training Adaptations in Resistance Trained Athletes
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 122
- 主要终点
- Examine the effects of C4 supplementation during resistance training by assessing muscle creatine levels
研究概览
简要总结
The purpose of this study is to examine the effects of a pre-workout dietary supplement during resistance training on training adaptations.
详细描述
A number of nutritional strategies have been developed to optimize nutrient delivery prior to exercise. This includes providing carbohydrate and a number of ergogenic nutrients prior to, during and/or following exercise. As a result, a number of pre-workout supplements have been developed to increase energy availability, promote vasodilation and/or positively affect exercise capacity. The purpose of this study is to investigate the effects of ingesting a pre-workout dietary supplement during resistance training on training adaptations.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •you are an apparently healthy and recreationally active male between the ages of 18 and
- •you will need to have at least six months immediate prior history of resistance training on the bench press and leg press or squat.
排除标准
- •you have a history of treatment for metabolic disease (i.e., diabetes), hypertension, hypotension, thyroid disease, arrhythmia and/or cardiovascular disease;
- •you are currently using prescription medications;
- •you have an intolerance to caffeine and/or other natural stimulants;
- •you have a history of smoking;
- •you drink excessively (i.e., 12 drinks per week or more);
研究组 & 干预措施
C4 Extreme
One dose of 12 grams (powder mixed with water): 1500 mg beta alanine, 1000 mg creatine nitrate, 1000 mg arginine alpha-ketoglutarate, 250 mg vitamin C, 150 mg N-Acetyl-Tyrosine, 135 mg caffeine, 7.5 mg L-Dopa, 30 mg vitamin B3, 10 mg Bitter Orange (Citrus Aurantium) fruit standardized for 30% synephrine (Advantra Z), 0.5 mg vitamin B6, 0.25 mg vitamin B9, and 0.035 mg vitamin B12.
干预措施: C4 Extreme, C4 Extreme (without Advantra Z) (Dietary Supplement)
C4 Extreme (without Advantra Z)
One dose of 12 grams (powder mixed with water): 1500 mg beta alanine, 1000 mg creatine nitrate, 1000 mg arginine alpha-ketoglutarate, 250 mg vitamin C, 150 mg N-Acetyl-Tyrosine, 135 mg caffeine, 7.5 mg L-Dopa, 30 mg vitamin B3, 0.5 mg vitamin B6, 0.25 mg vitamin B9, and 0.035 mg vitamin B12.
干预措施: C4 Extreme, C4 Extreme (without Advantra Z) (Dietary Supplement)
Placebo
One dose of flavored placebo (powder mixed with water)
干预措施: C4 Extreme, C4 Extreme (without Advantra Z) (Dietary Supplement)
结局指标
主要结局
Examine the effects of C4 supplementation during resistance training by assessing muscle creatine levels
时间窗: Eight weeks
Examine the effects of C4 supplementation during resistance training by assessing muscle carnosine levels
时间窗: Eight weeks
Examine the effects of C4 supplementation during resistance training by assessing body water
时间窗: Eight weeks
Examine the effects of C4 supplementation during resistance training by assessing body composition
时间窗: Eight weeks
Examine the effects of C4 supplementation during resistance training by assessing macronutrient intake
时间窗: Eight weeks
Examine the effects of C4 supplementation during resistance training by assessing 1 RM (repetition maximum) strength
时间窗: Eight weeks
Examine the effects of C4 supplementation during resistance training by assessing anaerobic sprint capacity
时间窗: Eight weeks
Examine the effects of C4 supplementation during resistance training by assessing cognitive function (i.e., Stroop Color and Word Test, Word Recall Test and Readiness to perform VAS)
时间窗: Eight weeks
次要结局
- Record side effects to evaluate safety(Eight weeks)
- Measure standard clinical chemistry panels in the blood to evaluate safety(Eight weeks)
- Measure heart rate to evaluate safety(Eight weeks)
- Measure blood pressure to evaluate safety(Eight weeks)