Intervention to Support Participation in Regular Exercise in the Elderly (INSPIRE)

Not Applicable

• Conditions: Chronic Illnesses
• Interventions: Behavioral: Physical activity plus positive affect; Behavioral: Physical activity plus education

• Registration Number: NCT02464254
• Lead Sponsor: Weill Medical College of Cornell University

Brief Summary

The investigators will conduct a 1-year prospective and randomized study to evaluate the initial efficacy of positive affect vs. an educational control to motivate physical activity in older adults with high burdens of chronic disease.

Detailed Description

Older adults with multiple chronic diseases are at high risk for both disability and adverse clinical events, outcomes that can be improved with physical activity, but there have been no trials to establish physical activity recommendations or clinical guidelines for this vulnerable population. A recent randomized controlled trial conducted by Dr. Peterson established the efficacy of inducing positive affect-a feeling of happiness and well-being-in motivating physical activity in older adults with cardiovascular disease. This new randomized controlled trial will pilot test the a new PAIRE (Positive Affect Induction for Regular Exercise) intervention that is specific to older adults with multiple high-risk chronic illnesses versus an educational control group. This work is innovative because it will translate the benefits of a proven intervention focused on positive affect to increase physical activity in older adults with multiple high-risk chronic illnesses, one that is tailored to the clinical and psychosocial challenges of this particularly vulnerable population. This work is significant because an effective intervention promoting physical activity will improve outcomes for older adults with multiple high-risk chronic diseases, and currently one does not exist.

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study First Submitted: 2015-06-02
• Study First Submitted QC: 2015-06-03
• Study First Posted: 2015-06-08
• Study Start: 2016-04
• Status Verified: 2019-06
• Last Update Submitted: 2019-06-19
• Last Update Posted: 2019-06-21
• Primary Completion: 2019-12-30
• Study Completion: 2020-12-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Charlson Index greater or equal to 3

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Exclusion Criteria

1. Cognitive impairment
2. Inability to walk
3. < 12 month anticipated survival
4. enrollment in other behavioral programs
5. lack of medical approval to participate
6. substance/alcohol dependence or participation in a substance abuse treatment program within 12 months
7. major psychiatric illness.

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Physical activity plus positive affect	Physical activity plus positive affect	Subjects will be randomized to a physical activity goal and the positive affect component
Physical activity plus positive affect	Physical activity plus education	Subjects will be randomized to a physical activity goal and the positive affect component
Physical activity plus education	Physical activity plus education	Subjects will be randomized to a physical activity goal and education

Primary Outcome Measures

Name	Time	Method
Kilocalories/week assessed by Objective measure of activity with accelerometry	baseline to 12 months	FitBit

Secondary Outcome Measures

Name	Time	Method
Kilocalories/week assessed by Subjective measure of activity by self-report	baseline to 12 months
Function/disability assessed by objective and subjective reports of functional ability	baseline to 12 months

Trial Locations

Locations (1)

Weill Cornell Medical College; 🇺🇸 New York, New York, United States