Treatment Initiation and Participation Program (TIP)
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Depression
- Sponsor
- Weill Medical College of Cornell University
- Enrollment
- 231
- Locations
- 2
- Primary Endpoint
- Brief Medication Questionnaire
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
The study is a randomized controlled trial to test the usefulness of a brief intervention to improve adherence to antidepressant medication prescribed to older adults in a primary care setting. Study will be conducted at Weill Cornell and University of Michigan.
Detailed Description
The intervention is a brief, psychosocial intervention designed to be an adjunct to pharmacotherapy prescribed by a primary care physician. It includes psychoeducation, problem solving and development of goals and a personalized adherence strategy. The intervention includes three 30 minute sessions during the first 6 weeks of treatment and a follow-up phone call two weeks later.
Investigators
Jo Anne Sirey
Associate Professor
Weill Medical College of Cornell University
Eligibility Criteria
Inclusion Criteria
- •Age: 65 and older; Newly prescribed antidepressant medication by PCP (within past 10 days); Has not been prescribed antidepressant medication in previous 6 months.
Exclusion Criteria
- •High suicide risk, i.e. intent or plan to attempt suicide Presence of alcohol abuse, substance abuse, psychotic disorder or, bipolar disorder as observed on the SCID, are excluded; Dementia: MMSE below 24, clinical assessment, or medication; Inability to speak English; Aphasia interfering with communication; Terminal illness or current chemotherapy
Outcomes
Primary Outcomes
Brief Medication Questionnaire
Time Frame: 12 week Follow up
Participants randomized to the TIP intervention will be significantly more likely to be adherent (take more than 80% of prescribed doses) to antidepressant treatment at 6-week follow-up (immediately after the intervention is completed) and 12-week follow-up (6 weeks after intervention is completed) as compared to older adults randomized to the Treatment as usual control condition.
Secondary Outcomes
- Hamilton Depression Rating Scale(12 weeks)