Study between heavy levobupivacaine(local anaesthetic) and heavy bupivacaine(local anaesthetic) with fentanyl(opiod analgesic) when injected in csf of spinal cord in caesarean secton to know which drug is better in terms of faster effect and better safety between these two.
Not Applicable
Completed
- Conditions
- Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium
- Registration Number
- CTRI/2023/06/053561
- Lead Sponsor
- nil
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
ASA physical status I and II
Heights 135-165 cms
period of gestation more than 37 weeks
Exclusion Criteria
Patient refusal
Patients with coagulopathy
patients on anticoagulants and antiplatelets
patients wiith local skin infection at the site of injection
History of allergy to amide local anaesthetics or fentanyl
ASA III or more
patients with spine disorder
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome of study is regression of motor effect. <br/ ><br>Timepoint: AT 120 minutes after injecting study drug <br/ ><br>
- Secondary Outcome Measures
Name Time Method To determine the intraoperative haemodynamic changes <br/ ><br>Timepoint: At interval of 1 minute for first five minutes,then after every 5 minutes upto 20 minutes and then every 15 minutes throughout surgery period till it lasts
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms differentiate hyperbaric levobupivacaine from bupivacaine-fentanyl combinations in spinal anesthesia for cesarean sections?
How does the efficacy of hyperbaric levobupivacaine compare to bupivacaine with fentanyl in achieving rapid sensory-motor block during CTRI/2023/06/053561?
Which biomarkers correlate with improved postoperative analgesia or reduced hypotension risk in spinal anesthesia using hyperbaric local anesthetics and fentanyl?
What are the safety profiles of hyperbaric levobupivacaine versus bupivacaine-fentanyl in managing maternal hemodynamics during elective cesarean sections?
How do hyperbaric levobupivacaine and bupivacaine-fentanyl compare to other local anesthetic-opioid combinations (e.g., ropivacaine-morphine) in obstetric spinal anesthesia?