Erythropoietin Resistance in Anemia of Chronic Kidney Disease

Completed

• Conditions: Anemia; Kidney Failure; Erythropoietin

• Registration Number: NCT00526747
• Lead Sponsor: Duke University

Brief Summary

Our goal of this pilot project is to identify inflammatory biomarkers that correlate with epo-resistance among CKD patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-08
• Study First Submitted: 2007-09-06
• Study First Submitted QC: 2007-09-06
• Study First Posted: 2007-09-10
• Primary Completion: 2008-06
• Study Completion: 2008-06
• Status Verified: 2008-11
• Last Update Submitted: 2013-04-09
• Last Update Posted: 2013-04-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

• prevalent patients greater than or equal to 18 years old with CKD defined as a glomerular filtration rate < 60 cc/min

Exclusion Criteria

• active GI bleeding or history of GI bleed in the prior 3 months
• uncontrolled hyperparathyroidism (PTH>500)
• untreated iron deficiency (transferrin saturation < 20% and ferritin < 100
• overt infection
• active hemolysis
• hemoglobinopathies
• known adverse response to erythropoietin
• prior kidney transplant
• aluminum toxicity

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (2)

Duke University Medical Center Anemia Clinic; 🇺🇸 Durham, North Carolina, United States

Durham Nephrology Anemia Clinic; 🇺🇸 Durham, North Carolina, United States