EUCTR2008-001462-81-IT进行中（未招募）1 期
Effects of Losartan versus Nebivolol versus the association of both on the progression of aortic root dilation in Marfan Syndrome (MFS) with FBN1 gene mutations - ND
OSPEDALE POLICLINICO S. MATTEO0 个研究点开始时间: 2008年3月17日最近更新:
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •patients aged 12 months to 55 years without prior aortic surgery with a BSA-adjusted aortic root z score >/= 2.5.
- •Are the trial subjects under 18? yes
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •prior aortic surgery and/or dissection, aortic root diameter at the level of the sinuses of valsalva >/= 5 cm, planned aortic surgery within 6 months of enrolment for a rate of ARD progression > 5 mm/year even in pts with ARD less than 5 cm, ...
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