Study to compare effects of timolol eye drops versus oral propranolol in patients of infantile hemangioma
Phase 3
- Conditions
- Health Condition 1: D180- Hemangioma
- Registration Number
- CTRI/2020/03/023700
- Lead Sponsor
- Mahatma Gandhi Mission Ethics Committee for Research on Human Subjects
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patient parents willing to undergo treatment and ready to bring the patient for followup.
Focal and localized hemangioma.
Exclusion Criteria
Patients who have contraindications for beta blockers.
Extra cutaneous and multifocal hemangioma.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Decrease in size. <br/ ><br>Change in colour <br/ ><br>change in consistency <br/ ><br>Change in surface <br/ ><br>Change in depth by ultrasoundTimepoint: Once a week for first two weeks, once every two weeks for next two months and then once a month thereafter for 6 months
- Secondary Outcome Measures
Name Time Method Side effects of propranolol are hypotension, bradycardia, hyperkalemia, bronchospasm, hypoglycemia, restless sleep, constipation, diarrhea, hypothermia, nausea,vomiting, gastro esophageal reflux and cold extremities.Timepoint: Once a week for first two weeks, once every two weeks for next two months and then once a month thereafter for 6months.