A Study on Hemodynamic Relationship Including Cerebral Blood Flow Using Phase Contrast and Signal Intensity Gradient of Brain Magnetic Resonance Imaging, and Carotid Doppler Ultrasound

Chonbuk National University Hospital1 site in 1 country30 target enrollmentSeptember 3, 2020

ConditionsCerebral Blood Flow

Overview

Phase: N/A
Intervention: Not specified
Conditions: Cerebral Blood Flow
Sponsor: Chonbuk National University Hospital
Enrollment: 30
Locations: 1
Primary Endpoint: Cerebral blood flow correlation
Last Updated: 5 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Cerebral blood flow measurement, which is applied to patients with cerebrovascular-related diseases, provides useful information about hemodynamic status. There was a method using Doppler ultrasound and phase contrast (PC) MRI, but it was not widely used in clinical practice due to limitations in reproducibility between examiners, complexity of procedure, and time-intensive protocol. We intend to measure cerebral blood flow through the signal-intensity gradient (SIG) technique using Time-of-Flight (TOF) of brain magnetic resonance imaging, which can compensate for the shortcomings of the existing research methods. In addition, by analyzing the correlation with the previous methods, Doppler ultrasound and PC MRI, we will evaluate the effectiveness of our new method.

Registry

clinicaltrials.gov

Start Date

September 3, 2020

End Date

January 31, 2021

Last Updated

5 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Chonbuk National University Hospital

Responsible Party

Principal Investigator

Chan-Hyuk Lee

Professor

Chonbuk National University Hospital

Eligibility Criteria

Inclusion Criteria

•Patients 18 years of age or older who have been admitted to the neurology department due to a stroke, and those who have already performed brain magnetic resonance imaging
•Among the patients (1) who underwent carotid artery Doppler ultrasound
•Patients who fully understand the research objectives and procedures and wish to participate in clinical research voluntarily
•If a patient is not fully understood due to a decrease in awareness or consciousness, the consent of the legal representative is required

Exclusion Criteria

•Patients whose extracranial artery occlusion or severe stenosis was confirmed in brain magnetic resonance images.
•Those who judge that the subject is unsuitable for participation in clinical research due to other reasons.