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Resistance Training in Adults With Obesity

Not Applicable
Completed
Conditions
Overweight and Obesity
Interventions
Other: High-repetition resistance training
Other: Moderate-repetition resistance training
Registration Number
NCT05092061
Lead Sponsor
Norwegian University of Science and Technology
Brief Summary

The purpose of this project is two-fold: (1) to assess if two different resistance training protocols elicit different responses in the acute phase and (2) to assess if the same two different protocols will elicit different long-term responses on muscular strength, body composition and cardiometabolic health. The project will include 30 adults with obesity (defined as BMI ≥ 30 or abdominal obesity according to the International Diabetes Federation). In the acute phase blood lactate, heart rate, enjoyment and perceived exertion will be assessed after the two resistance training protocols. In addition, the mean 24-h blood glucose concentration after exercise will be compared between the two protocols.

For the long-term effects blood markers of cardiometabolic health, blood pressure, body composition, objectively measured physical activity and physical fitness will be assessed before and after the intervention. Also, perceived health-related quality of life will be assessed before and after the intervention.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
31
Inclusion Criteria
  • Obesity (BMI ≥ 30) or
  • Central obesity (defined according to the International Diabetes Federation).
Exclusion Criteria
  • Unstable angina
  • recent cardiac infarction (last 4 weeks)
  • uncompensated heart failure
  • severe valvular illness
  • pulmonary disease
  • uncontrolled hypertension
  • kidney failure
  • orthopaedic/neurological limitations
  • cardiomyopathy
  • planned operations during the research period
  • participation in a parallel study

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
High-repetition resistance trainingHigh-repetition resistance trainingThe participants will undergo a full-body resistance training protocol with high repetitions (15+), low load (\<60% of 1RM), and short rest between sets (30s). Training will be undertaken three times per week.
Moderate-repetition resistance trainingModerate-repetition resistance trainingThe participants will undergo a full-body resistance training protocol with moderate repetitions (6-12), moderate load (70-85% of 1RM), and moderate rest between sets (60-90s). Training will be undertaken three times per week.
Primary Outcome Measures
NameTimeMethod
Glycated haemoglobin (HbA1c)7 weeks
Secondary Outcome Measures
NameTimeMethod
Blood lipid concentration7 weeks
Fasting glucose7 weeks
C-reactive protein7 weeks
Systolic blood pressure7 weeks
Diastolic blood pressure7 weeks
Health-Related Quality of Life7 weeks

Using the Short-Form 36 survey and Satisfaction with Physical Function and Appearance Survey

Body fat7 weeks

Measured by bioelectrical impedance (InBody 770)

Fat-free mass7 weeks

Measured by bioelectrical impedance (InBody 770)

Waist circumference7 weeks
VO2max (maximal aerobic capacity)7 weeks
Body mass7 weeks

Measured by bioelectrical impedance (InBody 770)

Visceral fat area7 weeks

Measured by bioelectrical impedance (InBody 770)

Muscular strength (1RM)7 weeks

Leg press and bench press

Rate of force development7 weeks

Measured by Kistler force plate

Muscular endurance7 weeks

Maximum number of repetitions using 50% of 1-RM

Physical activityBaseline (before intervention), 4 and 7 weeks.

Assessed at three timepoints throughout the intervention using SenseWear armband activity monitors and/or Personal Activity IntelligenceTM (using heart rate monitors and smart phone application).

Trial Locations

Locations (1)

Department of Circulation and Medical Imaging

🇳🇴

Trondheim, Norway

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