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临床试验/NCT05092061
NCT05092061已完成不适用

Acute and Chronic Effects of Two Different Types of Resistance Training on Cardiometabolic Health in Adults With Obesity

Norwegian University of Science and Technology2 个研究点 分布在 1 个国家目标入组 31 人开始时间: 2021年10月14日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
31
试验地点
2
主要终点
Glycated haemoglobin (HbA1c)

研究概览

简要总结

The purpose of this project is two-fold: (1) to assess if two different resistance training protocols elicit different responses in the acute phase and (2) to assess if the same two different protocols will elicit different long-term responses on muscular strength, body composition and cardiometabolic health. The project will include 30 adults with obesity (defined as BMI ≥ 30 or abdominal obesity according to the International Diabetes Federation). In the acute phase blood lactate, heart rate, enjoyment and perceived exertion will be assessed after the two resistance training protocols. In addition, the mean 24-h blood glucose concentration after exercise will be compared between the two protocols.

For the long-term effects blood markers of cardiometabolic health, blood pressure, body composition, objectively measured physical activity and physical fitness will be assessed before and after the intervention. Also, perceived health-related quality of life will be assessed before and after the intervention.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Obesity (BMI ≥ 30) or
  • Central obesity (defined according to the International Diabetes Federation).

排除标准

  • Unstable angina
  • recent cardiac infarction (last 4 weeks)
  • uncompensated heart failure
  • severe valvular illness
  • pulmonary disease
  • uncontrolled hypertension
  • kidney failure
  • orthopaedic/neurological limitations
  • cardiomyopathy
  • planned operations during the research period
  • participation in a parallel study

结局指标

主要结局

Glycated haemoglobin (HbA1c)

时间窗: 7 weeks

次要结局

  • Fasting glucose(7 weeks)
  • Blood lipid concentration(7 weeks)
  • C-reactive protein(7 weeks)
  • Systolic blood pressure(7 weeks)
  • Diastolic blood pressure(7 weeks)
  • Body fat(7 weeks)
  • Fat-free mass(7 weeks)
  • Waist circumference(7 weeks)
  • VO2max (maximal aerobic capacity)(7 weeks)
  • Body mass(7 weeks)
  • Visceral fat area(7 weeks)
  • Muscular strength (1RM)(7 weeks)
  • Rate of force development(7 weeks)
  • Muscular endurance(7 weeks)
  • Physical activity(Baseline (before intervention), 4 and 7 weeks.)
  • Health-Related Quality of Life(7 weeks)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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