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Clinical Trials/NCT05092061
NCT05092061
Completed
Not Applicable

Acute and Chronic Effects of Two Different Types of Resistance Training on Cardiometabolic Health in Adults With Obesity

Norwegian University of Science and Technology1 site in 1 country31 target enrollmentOctober 14, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Overweight and Obesity
Sponsor
Norwegian University of Science and Technology
Enrollment
31
Locations
1
Primary Endpoint
Glycated haemoglobin (HbA1c)
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

The purpose of this project is two-fold: (1) to assess if two different resistance training protocols elicit different responses in the acute phase and (2) to assess if the same two different protocols will elicit different long-term responses on muscular strength, body composition and cardiometabolic health. The project will include 30 adults with obesity (defined as BMI ≥ 30 or abdominal obesity according to the International Diabetes Federation). In the acute phase blood lactate, heart rate, enjoyment and perceived exertion will be assessed after the two resistance training protocols. In addition, the mean 24-h blood glucose concentration after exercise will be compared between the two protocols.

For the long-term effects blood markers of cardiometabolic health, blood pressure, body composition, objectively measured physical activity and physical fitness will be assessed before and after the intervention. Also, perceived health-related quality of life will be assessed before and after the intervention.

Registry
clinicaltrials.gov
Start Date
October 14, 2021
End Date
February 28, 2022
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Obesity (BMI ≥ 30) or
  • Central obesity (defined according to the International Diabetes Federation).

Exclusion Criteria

  • Unstable angina
  • recent cardiac infarction (last 4 weeks)
  • uncompensated heart failure
  • severe valvular illness
  • pulmonary disease
  • uncontrolled hypertension
  • kidney failure
  • orthopaedic/neurological limitations
  • cardiomyopathy
  • planned operations during the research period

Outcomes

Primary Outcomes

Glycated haemoglobin (HbA1c)

Time Frame: 7 weeks

Secondary Outcomes

  • Fasting glucose(7 weeks)
  • Blood lipid concentration(7 weeks)
  • C-reactive protein(7 weeks)
  • Systolic blood pressure(7 weeks)
  • Diastolic blood pressure(7 weeks)
  • Body fat(7 weeks)
  • Fat-free mass(7 weeks)
  • Waist circumference(7 weeks)
  • VO2max (maximal aerobic capacity)(7 weeks)
  • Body mass(7 weeks)
  • Visceral fat area(7 weeks)
  • Muscular strength (1RM)(7 weeks)
  • Rate of force development(7 weeks)
  • Muscular endurance(7 weeks)
  • Physical activity(Baseline (before intervention), 4 and 7 weeks.)
  • Health-Related Quality of Life(7 weeks)

Study Sites (1)

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