Phenylephrine Versus Eyelid Taping for Muller's Muscle-Conjunctival Resection (MMCR) Evaluation

Phase 4

Recruiting

• Conditions: Ptosis, Eyelid

• Registration Number: NCT05890027
• Lead Sponsor: University of Miami

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-5-25
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Inclusion Criteria:<br><br> - Individuals diagnosed with ptosis undergoing conjunctival Muller's muscle resection<br> evaluation.<br><br> - Individuals who can tolerate and have no hypersensitivity to phenylephrine 2.5%<br> ophthalmic solution.<br><br> - Individuals who can tolerate eye-drop medications.<br><br> - Individuals who are physically able to take a tangent screen visual field test.<br><br> - Age: Adults who can comprehend the instructions and procedures (18-90 years old).<br><br>Exclusion Criteria:<br><br> - This study will not incorporate any of the following at-risk populations: adults<br> unable to consent, individuals who are not yet adults, pregnant women, prisoners.<br><br> - This study will not include participants who refuse to consent.<br><br> - This study will not include participants who are too tired or unable to take a<br> tangent screen visual field test (see Risk to Subjects).<br><br> - This study will not include individuals who may not be able to tolerate<br> phenylephrine 2.5% ophthalmic solution.<br><br> - Specifically, those with a past medical history of bradycardia, hypotension,<br> autonomic dysfunction, or severe cardiovascular disease<br><br> - This study will not include individuals who consume drugs contraindicated in<br> phenylephrine use: Ergot Derivatives (Vasoconstrictive CYP3A4 Substrates),<br> Iobenguane Radiopharmaceutical Products, Kratom, Lisuride, Monoamine Oxidase<br> Inhibitors

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in ptosis as measured by the tangent screen visual field test;Change in ptosis as measured by the margin to reflex distance 1 (MRD1)