Clinical Study of Titrating PEEP of Different Methods on Right Heart Function
- Conditions
- ARDS, Human
- Registration Number
- NCT03845556
- Lead Sponsor
- Southeast University, China
- Brief Summary
To observe the influence of different methods titrating PEEP on right heart function and pulmonary artery pressure in ARDS patients .
- Detailed Description
30 patients who diagnosed as ARDS were included in this study.Then set PEEP with respectively ARDS net 、EIT and Esophageal Pressure in Breathing Machine . Recorded diameter of right and left ventricular TAM TAPSE pulmonary artery pressure.Objective to evaluate the correlation between the level of PEEP in three methods and the right heart function and pulmonary artery pressure in ARDS patients .
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 30
- Patients admitted to ICU diagnosed of modecate to severe ARDS (Berlin criteria)
- Patients age between 18 years old and 80 years
- Patients with chronic respiratory diseases such as COPD.
- Ventilated because of oesophageal surgery in the previous 12months.
- Patients who cannot obtain clear ultrasound images due to thoracic surgery ,massive pleural effusion.
- Oesophageal bleeding in previous 30 days history of oesophageal varices.
- Facial trauma and surgery.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method the function of right heart and pulmonary artery pressure 2018.4-2019.3 Systolic Pulmonary Artery Pressure TAPSE or Tricuspid Annular Motion orTricuspid annular plane systolic excursion or right ventricular diameter or right left ventricular diameter ratio in diffrient PEEP
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Zhongda Hospital
🇨🇳Nanjing, Jiangsu, China