Comparison of PEEP Effect on Perioperative Oxygenation and Postoperative Pulmonary Complications in Lithotomy Position

• Conditions: Lung Ultrasound; Positive End Expiratory Pressure
• Interventions: Diagnostic Test: PEEP; Diagnostic Test: ZEEP

• Registration Number: NCT05261295
• Lead Sponsor: Ankara City Hospital Bilkent

Brief Summary

The main purpose of the study is to compare the effectiveness of PEEP application in terms of perioperative oxygenation level in the use of classical LMA and i-gel, which is often preferred. The secondary aim is to compare parameters such as gastric insufflation and the rate of postoperative pulmonary complication development in the case of PEEP with two supraglottic airway devices.

Detailed Description

Not available

Study Timeline

• Status Verified: 2022-02
• Study First Submitted: 2022-02-11
• Study First Submitted QC: 2022-02-25
• Last Update Submitted: 2022-02-25
• Study Start: 2022-03
• Study First Posted: 2022-03-02
• Last Update Posted: 2022-03-02
• Primary Completion: 2022-06
• Study Completion: 2022-07

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 128

Inclusion Criteria

• ASA I-III
• Patients who will undergo transurethral resection of the bladder and prostate taken in the lithotomy position, ureter and kidney stone operations with ureteroscopy

Exclusion Criteria

• Heart failure (ejection fraction < 40%),
• unstable hemodynamic conditions
• Having neck or upper respiratory tract pathology,
• have an increased risk of aspiration (gastroesophageal reflux disease, full stomach, acidity),
• obesity (body mass index≥30 kg m-2)
• Patients with poor tooth structure will also be excluded.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Classical LMA	PEEP	Patients who received general anesthesia with classical LMA
Classical LMA	ZEEP	Patients who received general anesthesia with classical LMA
i-Gel	PEEP	Patients who received general anesthesia with i-Gel
i-Gel	ZEEP	Patients who received general anesthesia with i-Gel

Primary Outcome Measures

Name	Time	Method
LUS score preop	Baseline	Loss of ventilation will be evaluated by calculating the LUS score. Each region will be scored according to the LUS model as follows: Presence of lung deviation with lines or less than two isolated B-lines is scored as 0; 1 point in the presence of more than one well-defined B line; presence of more than one combined B line, 2 points; and when a tissue pattern characterized by dynamic air bronchograms (lung consolidation) is presented, the score is 3. The worst ultrasound pattern observed in each region will be recorded and used to calculate the sum of the scores.
LUS score postoperative	postoperative 1.hour	Loss of ventilation will be evaluated by calculating the LUS score. Each region will be scored according to the LUS model as follows: Presence of lung deviation with lines or less than two isolated B-lines is scored as 0; 1 point in the presence of more than one well-defined B line; presence of more than one combined B line, 2 points; and when a tissue pattern characterized by dynamic air bronchograms (lung consolidation) is presented, the score is 3. The worst ultrasound pattern observed in each region will be recorded and used to calculate the sum of the scores.