Comparison of the effects of different PEEP (positive end-expiratory pressure) levels on cerebral oxygen saturation in patients undergoing laparoscopic cholecystectomy

Not Applicable

Completed

• Conditions: CO2 pneumoperitoneum; Cerebral oxygen saturation; Anaesthesiology - Other anaesthesiology; Surgery - Surgical techniques

• Registration Number: ACTRN12615000581561
• Lead Sponsor: Konya Training and Research Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-06-03
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 105

Inclusion Criteria

Scheduled for elective laparoscopic cholecystectomy.

ASA physical status I and II.

Exclusion Criteria

Patients with morbid obessity (body mass index > 30 kg/m2), Patients with cerebrovascular disease,
Patients with respiratory disease,
Patients with cardiovascular disease,
Patients with metabolic disease
patients with acute cholecystitis.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cerebral oxygen saturation values as assessed by near infrared spectroscopy[Cerebral oxygen saturation values were continuously recorded from awake status to tracheal extubation <br>(basal, after induction, after intubation, immediately after pneumoperitoneum, every 5 minutes during pneumoperitoneum, immediately after desufflation of CO2, at the end of surgery, after). ]

Secondary Outcome Measures

Name	Time	Method
Hemodynamic parameters (HR, MBP) continuously recorded from the anaesthetic machine monitors.[Hemodynamic parameters (HR, MBP) were continuously recorded from awake status to tracheal extubation (basal, after induction, after intubation, immediately after pneumoperitoneum, every 5 minutes during pneumoperitoneum, immediately after desufflation of CO2, at the end of surgery, after). ];Peak inspiratory pressure (PIP) values continuously recorded from the anaesthetic machine monitors.[Peak inspiratory pressure (PIP) were recorded (after intubation, immediately after pneumoperitoneum, every 5 minutes during pneumoperitoneum, immediately after desufflation of CO2, at the end of surgery, after).]