Detection of precancer cervical lesions with methylation markers in urine
Recruiting
- Conditions
- Methylation markers, cervix carcinoma, CIN2, CIN3, CIN, urine analysis
- Registration Number
- NL-OMON23501
- Lead Sponsor
- VUmc
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
>18 years old
- eligible for LLETZ
Exclusion Criteria
- other cancer elsewhere
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Concordance between HPV DNA detection and DNA methylation analysis in urine and a cervicovaginal self sample
- Secondary Outcome Measures
Name Time Method Performance of biomarkers in urine for detection of CIN2+ or CIN3+, and compared with the performance of this test in cervicovaginal self samples <br>