Discovery of biomarkers for cervical neoplasia by genome-wide gene-expression profiling
Recruiting
- Conditions
- (premaligant lesions) of cervical cancercervical neoplasia10013364
- Registration Number
- NL-OMON40971
- Lead Sponsor
- niversitair Medisch Centrum Sint Radboud
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 165
Inclusion Criteria
All groups: Age>=18 years
Group 1. undergoing surgery with removal of the cervix for benign abnormalities.
Group 2. undergoing loop electrosurgical excision procedure during colposcopy for (suspected) cervical intraepithelial neoplasia lesion
Group 3. undergoing anesthetized physical examination or surgery in case of (suspected) cervical cancer
Exclusion Criteria
Pregnant during the tissue sampling or pregnancy in the last 3 months
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study parameter is the genome-wide expression profile of the different<br /><br>samples collected in this study, pooled by groups of CIN lesions, cervical<br /><br>cancer and normal cervical tissue. </p><br>
- Secondary Outcome Measures
Name Time Method <p>n.a.</p><br>