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Effects of oral clonidine pre-medication on intra-operative blood loss during caesarean section under sub-arachnoid block

Not Applicable
Conditions
Pregnancy and Childbirth
Registration Number
PACTR202403873496250
Lead Sponsor
Self
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
Female
Target Recruitment
160
Inclusion Criteria

Normotensive and mild to moderate hypertensive (controlled) pregnant women aged 18 to 45 years who were scheduled for elective caesarean section under SAB at the study centre
Those who consented to participate in the study.

Exclusion Criteria

?Patients below age 18 and above age 45years.
?Grandmultiparous women (parity greater or equal to 5).
?Patients with complications of pregnancy such as: placenta praevia, Abruptio placentae, pre-eclampsia with BP = 160/110mmHg, Eclampsia, pregnancy-induced hypertension or chronic hypertension in pregnancy with BP = 160/110mmHg.
?Emergency Caesarean sections
?Patients with Cardiovascular /Respiratory diseases
?Renal/hepatic disease patients
?Multiple gestations.
?Patients that took antihypertensive <24 hours before surgery.
?History of allergy to the study drug.
?Patients with height less or equal to 1.0m.
?Patients with previous caesarean section(s).

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Volume of intra-operative blood loss
Secondary Outcome Measures
NameTimeMethod
Haemodynamic stability of patients, neonatal APGAR Scores, incidence of side effects like nausea, vomiting, shivering, sedation, hypotension etc. and the need for rescue analgesia
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