The effect of clonidine on hemodynamic complications of laparoscopy
Phase 3
- Conditions
- aparoscopic cholecystectomy.Calculus of gallbladder without cholecystitis
- Registration Number
- IRCT2013120111398N5
- Lead Sponsor
- Research deputy, Iran University of Medical Siences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
ASA grades II and III, both males and females, adult patients aged 18 to 65 years, with Controlled Hypertension (Systolic less than 140 and diastolic less than 90) scheduled Laparoscopic cholecystectomy surgeries.
Exclusion criteria: Lack of patient consent, history of bronchial asthma, patients allergic to clonidine, hypertensive and diabetic patients, severe coronary insufficiency, recent myocardial infection, concomitant use of monoamine oxidase inhibitors, tricyclic antidepressants or opioids.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mean arterial blood pressure. Timepoint: Before induction, in 1,5,10,15 and 20 minute after induction, and every 15 minute until the end of the operation. Method of measurement: Will be recorded by Automatic Hemodynamic Monitoring.
- Secondary Outcome Measures
Name Time Method Patient's pain intensity. Timepoint: Entrance to the recovery, 30, 60, 90 and 120 minutes postoperatively. Method of measurement: According to VAS rating score.