The efficacy of Simvastatin in maxillary sinus augmentatio

Phase 4

Conditions: bone loss in the posterior maxillary edentulous ridge.

Registration Number: IRCT20120127008830N5

Lead Sponsor: Vice chancellor for Research and Technology, Tehran University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 12

Inclusion Criteria

Patients with age over 18
Desiring to receive maxillary posterior implants
Not having sufficient bone determined on CBCT for dental implant
The patients are partially or completely toothless in the posterior maxilla
Patients who need bilateral maxillary sinus augmentation surgeries

Exclusion Criteria

Needing antibiotic prophylaxis for dental procedures
Any sinus pathology (acute or chronic) contraindicating the sinus graft surgery
Patients with systemic disease contraindicating any oral surgeries
Patients who smoke more than 10 cigarettes daily
Women who are pregnant or wish to become pregnant during the period of the study
Diseases or medications known to affect bone metabolism ,tissue regeneration and repair such as corticosteroids, bisphosphonates and etc
Patients with a history of alcoholism or drug abuse
Patients who have a history of cancer or radiation to the head and neck

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Alveolar bone height on Cone Beam Computed Tomograghy. Timepoint: Preoperative, immediately and 9 months after sinus graft. Method of measurement: Cone Beam Computed Tomography:Two lines which are the mesial and distal limits of the augmented area and a center point between these two lines were selected on Cone Beam Computed Tomographys that were taken. Alveolar bone height in these three lines measured and the average of these measurements was reported as mean alveolar bone height.;Alveolar bone density on Cone Beam Computed Tomograghy. Timepoint: preoperatively, immediately and at 9 months after sinus graft. Method of measurement: Cone Beam Computed Tomography.

Secondary Outcome Measures