Investigation of The Effect of Vitamin D Supplementation on Apical Lesion Healing Rate: Prospective, Randomized Clinical Trial
- Conditions
- vitamin D deficiency and apical periodontitisVitamin D, apical periodontitis, endodontics, fractal
- Registration Number
- TCTR20221020006
- Lead Sponsor
- RECEP TAYYIP ERDOGAN UNIVERSITY RECTORATE Scientific Research Projects Coordination Unit
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Active, not recruiting
- Sex
- Male
- Target Recruitment
- 70
1. Systemically healthy,
2. 25(OH) vitamin D level between 20-30 ng/ml,
3. Non-smoker
4. Male patients who do not take additional vitamin D supplements externally,
5. Devital, closed apex mandibular molar teeth with a periapical lesion of 5 mm or more involving only one root (referring to the largest diameter of the lesion).
1. 25(OD) vitamin D value < 20 ng / mL patients,
2.Female patients,
3. Patients with bone metabolism disease and/or patients using drugs (such as steroids, bisphosphonates) that will affect bone metabolism,
4. Patients with a history of radiotherapy,
5. Individuals with diabetes, chronic kidney failure and/or thyroid disease,
6. Patients with sclerosing osteitis, osteosclerosis or any bone pathology (cyst, tumor) in the quadrant of the tooth to be treated,
7. Generalized chronic periodontitis patients
8. Having a periodontal lesion smaller than 5 mm and a periodontal pocket deeper than 3 mm,
9. Developmental anomaly
10. Teeth with a combined lesion involving both roots.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method vitamin D AFTER BLOOD SAMPLE IS TAKEN kemiluminesans method
- Secondary Outcome Measures
Name Time Method periapical lesion healin after checkup appointments fractal analysis with Image J