Changes in Cerebral Oxygenation Based on Intraoperative Ventilation Strategy
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Posterior Spinal Fusion
- Sponsor
- Joseph D. Tobias
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Change in Cerebral Oxygenation Values Throughout the Procedure
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
The proposed research aims to investigate how different ventilation strategies may affect cerebral tissue oxygenation in the pediatric population. It will contribute to the literature exploring the NIRS monitoring device which is becoming increasingly utilized in a variety of anesthetic and critical care settings. It may help to guide clinical practice regarding optimal ventilation strategies, and how ventilation may be altered to correct suboptimal cerebral tissue oxygenation.
This prospective study will include 50 patients undergoing posterior spinal fusion that requires placement of an arterial cannulation. There will be no change in the anesthetic or perioperative care of these patients. Tissue and cerebral oxygenation will be monitored using near infrared spectroscopy (NIRS).
Investigators
Joseph D. Tobias
Chairman: Professor of Anesthesiology
Nationwide Children's Hospital
Eligibility Criteria
Inclusion Criteria
- •Any patient undergoing spinal surgery
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Change in Cerebral Oxygenation Values Throughout the Procedure
Time Frame: prior to induction of anesthesia in the awake patient and following four ventilation strategies (average time frame of 15 mins. to 5 hours)
Measured on the NIRS cerebral oxygenation monitor attached to the patient