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临床试验/NCT03363646
NCT03363646Unknown不适用

Italian National Multicenter Study on Infections in the Critically Ill Liver Transplant Recipient

Azienda Ospedaliero, Universitaria Pisana1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2018年7月1日最近更新:
适应症

试验速览

阶段
不适用
入组人数
200
试验地点
1
主要终点
Clinical

研究概览

简要总结

Despite major advances, infections remain one of the major causes of morbidity and mortality in patients undergoing orthotopic liver transplantation (OLT). Furthermore, data on the epidemiology, severity, and type of post-OLT infections nowadays available come from dated, monocentric, retrospective series. Finally, there is no available data focused on the critical OLT patient admitted to the Intensive Care Unit (ICU). Therefore this study was conceived (1) to describe incidence, severity, epidemiology and outcomes of infections recorded in OLT patients in the ICU (first or re-admission ); (2) to identify possible risk factors and (3) to report the type of the involved microorganism with their antibiotic sensitivity pattern

详细描述

The study will record clinical, epidemiological and microbiological data from the clinical files of OLT patients admitted at italian ICUs

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

Clinical

时间窗: 18 months

number and severity of infectious episodes

microbiological

时间窗: 18 months

describe the type of infectious agents

次要结局

  • Resistance(18 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Gianni Biancofiore

Associate Professor

University of Pisa

研究点 (1)

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