NCT06707727进行中(未招募)不适用
Characteristics and Prognostic Outcomes of Diaphragmatic Ultrasound in Myasthenia Gravis
First Affiliated Hospital of Chongqing Medical University1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2024年7月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中(未招募)
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- QMG changes
研究概览
简要总结
The goal of this observational study is to learn about the characteristics and prognostic outcomes of diaphragmatic ultrasound in myasthenia gravis. The main question it aims to answer is:
Does diaphragmatic ultrasound predict prognosis of myasthenia gravis in six months? Participants diagnosed as myasthenia gravis will take the diaphragm ultrasound examinations.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •1: Patients who seek treatment at the First Affiliated Hospital of Chongqing Medical University and have fluctuating skeletal muscle weakness and at least one of the following three conditions will be included: positive reaction to cholinesterase inhibitors
- •2: Serum positive antibodies against acetylcholine receptors, muscle specific kinases, or lipoprotein related proteins
- •3: Repeated electrical stimulation examination showed a decrease in wave amplitude.
排除标准
- •1: Patients with lung disease or heart failure, or a history of non-invasive ventilator or tracheotomy
结局指标
主要结局
QMG changes
时间窗: 6 months
次要结局
- Changes in medication type or dose(6 months)
- respiratory infection(6 months)
研究者
Fei Xiao
Prof.Fei Xiao
First Affiliated Hospital of Chongqing Medical University
研究点 (1)
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