跳至主要内容
临床试验/NCT06707727
NCT06707727进行中(未招募)不适用

Characteristics and Prognostic Outcomes of Diaphragmatic Ultrasound in Myasthenia Gravis

First Affiliated Hospital of Chongqing Medical University1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2024年7月1日最近更新:
适应症

试验速览

阶段
不适用
状态
进行中(未招募)
发起方
入组人数
100
试验地点
1
主要终点
QMG changes

研究概览

简要总结

The goal of this observational study is to learn about the characteristics and prognostic outcomes of diaphragmatic ultrasound in myasthenia gravis. The main question it aims to answer is:

Does diaphragmatic ultrasound predict prognosis of myasthenia gravis in six months? Participants diagnosed as myasthenia gravis will take the diaphragm ultrasound examinations.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

性别
All
接受健康志愿者

入选标准

  • 1: Patients who seek treatment at the First Affiliated Hospital of Chongqing Medical University and have fluctuating skeletal muscle weakness and at least one of the following three conditions will be included: positive reaction to cholinesterase inhibitors
  • 2: Serum positive antibodies against acetylcholine receptors, muscle specific kinases, or lipoprotein related proteins
  • 3: Repeated electrical stimulation examination showed a decrease in wave amplitude.

排除标准

  • 1: Patients with lung disease or heart failure, or a history of non-invasive ventilator or tracheotomy

结局指标

主要结局

QMG changes

时间窗: 6 months

次要结局

  • Changes in medication type or dose(6 months)
  • respiratory infection(6 months)

研究者

发起方
First Affiliated Hospital of Chongqing Medical University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Fei Xiao

Prof.Fei Xiao

First Affiliated Hospital of Chongqing Medical University

研究点 (1)

Loading locations...

相似试验

Characteristics and Prognostic Outcomes of... | 临床试验