NCT00297505已完成2 期
Serotonin, Impulsivity, and Cocaine Dependence Treatment
适应症
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 120
- 试验地点
- 2
- 主要终点
- The presence of cocaine metabolites in urine weekly.
研究概览
简要总结
The purpose of this study is to compare the effects of citalopram versus placebo given in the context of contingency management for cocaine dependence.
详细描述
Cocaine dependence continues to be a significant public health problem, for which there is no FDA approved pharmacotherapy. This study is a 12-week, double blind, placebo controlled trial of citalopram for cocaine dependence. The primary outcome measure is benzoylecgonine positive urines. Secondary measures of side effects and craving are also examined.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •male and female subjects age 18 to 50 who currently meet DSM-IV criteria for cocaine dependence.
- •female subjects: a negative pregnancy test
排除标准
- •current or past DSM-IV Axis I disorder other than substance abuse/dependence
- •any serious non-psychiatric medical illness requiring ongoing medical treatment
- •substance dependence other than cocaine within the last 3 months
- •negative urine drug screen for cocaine at time of testing
- •for female subjects: a positive pregnancy test
结局指标
主要结局
The presence of cocaine metabolites in urine weekly.
次要结局
- Retention rate and cocaine cravings weekly.
研究者
研究点 (2)
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