Comparison of Pretreatment with Combination of Ondansetron/Dexamethasone and Lidocaine on Propofol Injection Pain During Inductio

Phase 4

Completed

• Conditions: Patients ASA physical status I - III, age group between 20 and 60, who undergo elective surgery under general anesthesia.; Ondanstron, Dexamethasone, Lidocaine, Propofol

• Registration Number: TCTR20180822003
• Lead Sponsor: Department of Anesthesiology

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2018-07-01
• Study Start: 2018-08-22
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 178

Inclusion Criteria

1. Patients ASA physical status I - III
2. Age group between 20 and 60 years old
3. Undergo elective surgery under general anesthesia

Exclusion Criteria

1. History of 5-HT3 antagonist hypersensitivity
2. History of Propofol, egg and soybean hypersensitivity
3. Infected patient
4. History of lipid metabolism disorder
5. Chronic pain/analgesic received

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain intensity of propofol injection after pretreatment after propofol injection 10 seconds Numeric scale

Secondary Outcome Measures

Name	Time	Method
Side effect of pretreatment after injection of pretreatment Incidence of nausea and vomiting, perinium irritation