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Clinical Trials/NCT06664281
NCT06664281CompletedNot Applicable

Effects of Sprint Interval Training Combined with Remote Ischemic Preconditioning on Vascular Function in Young Women with Masked Obesity

Beijing Sport University1 site in 1 country44 target enrollmentStarted: February 28, 2023Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
44
Locations
1
Primary Endpoint
Intima-Media Thickness (IMT)

Study Overview

Brief Summary

Comparison of the effects of combined Sprint Interval Training (SIT) with Remote Ischemic Preconditioning (RIPC) and SIT on vascular function in young women with masked obesity.

Detailed Description

This is a randomized clinical trial of single-blind with 3 arms (control group, SIT group and SIT with RIPC group), in which a pre-treatment-posttest design has been used.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Prevention
Masking
Single (Participant)

Eligibility Criteria

Ages
18 Years to 30 Years (Adult)
Sex
Female
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Females aged between 18 and 30 years;
  • BMI within the normal range (18.5~24.9 kg/m²), BF% > 30%;
  • Participants with no clinically diagnosed contraindications for exercise, in good health, and not engaged in regular exercise, as determined by the health and physical activity questionnaire (based on the American College of Sports Medicine's guidelines for exercise testing and prescription).

Exclusion Criteria

  • History of cardiovascular diseases, including coronary heart disease, stroke, or peripheral arterial disease diagnosed through vascular imaging techniques;
  • Currently participating in other intervention studies, including dietary, nutritional, or psychological education programs;
  • Those with regular professional training;
  • Musculoskeletal disorders that make long-term exercise interventions unsuitable.

Outcomes

Primary Outcomes

Intima-Media Thickness (IMT)

Time Frame: 8 weeks

Changes in Intima media thickness before and after intervention.

Flow-Mediated Dilation (FMD)

Time Frame: 8 weeks

Changes in Flow-mediated dilation before and after Intervention. Brachial artery flow-mediated dilation (FMD) was measured by the UNEXEF high-resolution ultrasound vascular endothelial function analyzer.

Secondary Outcomes

  • Body Composition Indicator(8 weeks)
  • Human Morphometric i Indicators(8 weeks)
  • Blood Pressure (BP)(8 weeks)
  • Nitric Oxide (NO)(8 weeks)
  • Maximum Oxygen Uptake (VO2max)(8 weeks)

Investigators

Sponsor
Beijing Sport University
Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (1)

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