Effects of Sprint Interval Training Combined with Remote Ischemic Preconditioning on Vascular Function in Young Women with Masked Obesity
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 44
- Locations
- 1
- Primary Endpoint
- Intima-Media Thickness (IMT)
Study Overview
Brief Summary
Comparison of the effects of combined Sprint Interval Training (SIT) with Remote Ischemic Preconditioning (RIPC) and SIT on vascular function in young women with masked obesity.
Detailed Description
This is a randomized clinical trial of single-blind with 3 arms (control group, SIT group and SIT with RIPC group), in which a pre-treatment-posttest design has been used.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Prevention
- Masking
- Single (Participant)
Eligibility Criteria
- Ages
- 18 Years to 30 Years (Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Females aged between 18 and 30 years;
- •BMI within the normal range (18.5~24.9 kg/m²), BF% > 30%;
- •Participants with no clinically diagnosed contraindications for exercise, in good health, and not engaged in regular exercise, as determined by the health and physical activity questionnaire (based on the American College of Sports Medicine's guidelines for exercise testing and prescription).
Exclusion Criteria
- •History of cardiovascular diseases, including coronary heart disease, stroke, or peripheral arterial disease diagnosed through vascular imaging techniques;
- •Currently participating in other intervention studies, including dietary, nutritional, or psychological education programs;
- •Those with regular professional training;
- •Musculoskeletal disorders that make long-term exercise interventions unsuitable.
Outcomes
Primary Outcomes
Intima-Media Thickness (IMT)
Time Frame: 8 weeks
Changes in Intima media thickness before and after intervention.
Flow-Mediated Dilation (FMD)
Time Frame: 8 weeks
Changes in Flow-mediated dilation before and after Intervention. Brachial artery flow-mediated dilation (FMD) was measured by the UNEXEF high-resolution ultrasound vascular endothelial function analyzer.
Secondary Outcomes
- Body Composition Indicator(8 weeks)
- Human Morphometric i Indicators(8 weeks)
- Blood Pressure (BP)(8 weeks)
- Nitric Oxide (NO)(8 weeks)
- Maximum Oxygen Uptake (VO2max)(8 weeks)
