The Effect of High Intensity Interval Training on Maximal Oxygen Uptake and Risk Factors for Recurrent Stroke
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Stroke
- Sponsor
- Norwegian University of Science and Technology
- Enrollment
- 70
- Locations
- 1
- Primary Endpoint
- Maximal Oxygen Uptake
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
The purpose of this study is to examine if high intensity interval training after stroke is more effective than standard care to increase maximal oxygen uptake, reduce known risk factors for recurrent stroke and improve function.
Detailed Description
Stroke is a leading cause of adult disability. Well designed studies have shown that the majority of the stroke population have low aerobic capacity and many are inactive. This is negative for their health and well-being. Physical inactivity may increase their risk of having recurrent stroke. The optimal training mode and intensity to improve aerobic capacity after stroke are not clear. High intensity interval training (ie. 90-95% of peak heart rate) has been proven to be more beneficial than moderate and low intensity exercise in order to improve maximal oxygen uptake in patients with cardiac disease. The response from this training on aerobic capacity and physical function in the stroke population are not known.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Approved informed consent
- •Independent walking \> 2 minutes
- •First episode of stroke (ischemic or hemorrhagic)
- •Minimum 3 months post-stroke
- •Living in the community and able to travel to assessment and training site
- •Approval to participate from the study's responsible medical doctor
- •Modified Rankin Scale 0-3
Exclusion Criteria
- •Impaired cognitive function to give valid informed consent to participate
- •Instability of cardiac conditions (ie. serious rhythm disorder, valve malfunction)
- •Other conditions where test of maximal oxygen uptake is contraindicated
- •Poorly controlled hypertension (\>180/100), measured at rest
- •\> 5 years post stroke
- •Subarachnoid hemorrhage
- •Participating in other ongoing intervention study
- •Other serious illness influencing testing of cardiorespiratory fitness and function at 1 year follow-up
Outcomes
Primary Outcomes
Maximal Oxygen Uptake
Time Frame: 1 year after inclusion
A graded treadmill test of maximal oxygen uptake using a breath by breath ergospirometer
Secondary Outcomes
- Walking speed(8 weeks and 12 months after inclusion)
- Independence assessed by Functional Independence Measure (FIM)(8 weeks and 12 months after inclusion)
- Cognitive function assessed by Montreal Cognitive Assessment and Trail Making A and B(8 weeks and 12 months after inclusion)
- Walking distance(8 weeks and 12 months after inclusion)
- Leisure time activity and inactive time(8 weeks and 12 months after inclusion)
- Balance tested with the Bergs Balance Test(8 weeks and 12 months after inclusion)
- Change in Blood tests(8 weeks and 12 months after inclusion)
- Change in blood pressure (systolic and diastolic)(8 weeks and 12 months after inclusion)
- Self reported physical activity level assessed by International Physical Activity Questionnaire(8 weeks and 12 months after inclusion)