The Effect of High-intensity Interval Training and Moderate Intensity Continuous Training on Cardiopulmonary Functions in Chronic Heart Failure

Inha University Hospital1 site in 1 country60 target enrollmentJanuary 1, 2023

ConditionsChronic Heart Failure Cardiac Rehabilitation

Overview

Phase: N/A
Intervention: Not specified
Conditions: Chronic Heart Failure
Sponsor: Inha University Hospital
Enrollment: 60
Locations: 1
Primary Endpoint: Maximal or peak oxygen consumption (VO2max or VO2peak, same meaning) (kg/ml/min)
Status: Recruiting
Last Updated: 3 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The aim of this study is to investigate the effect of high-intensity interval training and moderate intensity continuous training on cardiopulmonary functions in chronic heart failure.

Detailed Description

enroll chronic heart failure patients into 3 randomized controlled group * high intensity interval training * moderate intensity continous training * control perform cardica rehab for 12 weeks, compare primary and secondary endpoints between baseline and 12 weeks results

Registry

clinicaltrials.gov

Start Date

January 1, 2023

End Date

December 31, 2025

Last Updated

3 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Inha University Hospital

Responsible Party

Principal Investigator

Joa KyungLim

professor, M.D. Ph.D

Inha University Hospital

Eligibility Criteria

Inclusion Criteria

•medically stable chronic heart failure
•NYHA II-III
•can perform cardiopulmonary exercise test
•after 3months with proper medication
•age 30 to 70
•ejection fraction\< 40%

Exclusion Criteria

•contraindication to cardiopulmonary exercise test
•musculoskeletal problem who cannot perform cardiopulmonary exercise test
•cognition deficit who cannot understand directions
•severe medial illness

Outcomes

Primary Outcomes

Maximal or peak oxygen consumption (VO2max or VO2peak, same meaning) (kg/ml/min)

Time Frame: compare baseline data with 12 weeks rehabilitation data

at the end of training, from baseline to 12 weeks

Secondary Outcomes

Anaerobic threshold (kg/ml/min)(compare baseline data with 12 weeks rehabilitation data)
6minute walk test (meter)(compare baseline data with 12 weeks rehabilitation data)
maximal heart rate (bpm)(compare baseline data with 12 weeks rehabilitation data)
systolic blood pressure (mmHg)(compare baseline data with 12 weeks rehabilitation data)
diastolic blood pressure (mmHg)(compare baseline data with 12 weeks rehabilitation data)
resting heart rate (bpm)(compare baseline data with 12 weeks rehabilitation data)
diastolic blood presure (mmHg)(compare baseline data with 12 weeks rehabilitation data)
depression scale by Patient Health Questionnaire(compare baseline data with 12 weeks rehabilitation data)
anxiety scale by Generalized Anxiety Disorder Scale(compare baseline data with 12 weeks rehabilitation data)
fatigue scale by fatigue severity scale(compare baseline data with 12 weeks rehabilitation data)
Quality of Life (QoL) questionnaire (MacNew)(compare baseline data with 12 weeks rehabilitation data)