Evaluation of the efficacy and safety of Doxycycline in combination with standard treatment in Covid-19 patients

Phase 3

• Conditions: Evaluation of the efficacy and safety of doxycycline in combination with standard treatment in Covid-19 patients..; COVID-19, virus identified; U07.1

• Registration Number: IRCT20191211045691N2
• Lead Sponsor: Yazd University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 30 November 2020

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Minimum age 18 and maximum age 80 years
Signing up the informed consent form
Do not take ?doxycycline during the past 5 days
Patients suspected of covid-19 based on clinical signs and manifestations of CT scan
Candidate for outpatient treatment

Exclusion Criteria

Patients hospitalized
Patients with hemodynamic instability
Patients with a history of allergic reaction or allergy to doxycycline
Second and third trimesters of pregnancy

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improve clinical symptoms including fever, shortness of breath, cough. Timepoint: Before starting the intervention and Days 1, 3, 7 and 14. Method of measurement: Questionnaire.;Blood o2 saturation. Timepoint: Before starting the intervention and Days 3 and 7. Method of measurement: Pulse oximetry device.

Secondary Outcome Measures

Name	Time	Method
Mortality. Timepoint: Day 14. Method of measurement: Questionnaire.;Hospitalization. Timepoint: Days 7 and 14. Method of measurement: Questionnaire.