Montelukast effect in acne treatment
Phase 3
Recruiting
- Conditions
- acne.Acne, unspecifiedL70.9
- Registration Number
- IRCT20191013045092N1
- Lead Sponsor
- Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 160
Inclusion Criteria
patients with moderate acne or acne that needs systemic antibiotic for treatment
patients have not been treated with systemic medications since 1 month ago and have not been treated with topical therapy since 2 weeks ago
married women accept to have contraception during treatment
Exclusion Criteria
history of hypersensitivity to the mentioned drugs
inability to come regularly for follow up
disagree to continue treatment
under 15 and above 35 years old
patients with acne conglobata and acne fulminans
recieving medications that have interaction with doxycycline and montelukast
pregnancy and lactation
using herbal therapy
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Acne severity. Timepoint: before treatment and 1,2,3 months after treatment. Method of measurement: Global acne grading system,burke and cunliffe and counting total lesion count.;Acne severity. Timepoint: before treatment and 3 months after treatment. Method of measurement: investigator global assessment score.
- Secondary Outcome Measures
Name Time Method Response to treatment. Timepoint: before treatment and 3 months after treatment. Method of measurement: asking patients.;The effect of acne on the patient's life. Timepoint: before treatment and 3 months after treatment. Method of measurement: Cardiff Acne disability index.