PAthwAy of Dyspneic patIent in Emergency in France

Not yet recruiting

• Conditions: Acute Dyspnea

• Registration Number: NCT06509854
• Lead Sponsor: Pr. Nicolas GIRERD

Brief Summary

This observational retrospective multi-center study focuses on patients treated for acute dyspnea by emergency medical teams. The primary objective is to identify factors associated with the risk of mortality and rehospitalization in these patients. This evaluation will be conducted both overall and within specific subgroups of interest, including gender (men/women), age categories, mode of admission, and comorbidities.

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-07
• Study First Submitted: 2024-07-04
• Study First Submitted QC: 2024-07-18
• Last Update Submitted: 2024-07-18
• Study First Posted: 2024-07-19
• Last Update Posted: 2024-07-22
• Study Start: 2024-09-30
• Primary Completion: 2025-09-30
• Study Completion: 2031-09-30

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 89700

Inclusion Criteria

• Man or women aged 18 years and older.
• Patients with acute dyspnea managed by a medical emergency team at the investigator centers between 2010 and 2021.

Exclusion Criteria

• Cardiorespiratory arrest before emergency department management.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
All-cause post-hospitalization mortality and rehospitalization	Within 5 years following hospital discharge	Composite endpoint of all-cause post-hospitalization mortality and rehospitalization

Secondary Outcome Measures

Name	Time	Method
All-cause mortality and specific mortality (cardiovascular and non-cardiovascular).	Within 5 years following hospital discharge	Assessed by: Composite endpoint of all-cause mortality and specific mortality (cardiovascular and non-cardiovascular) with outcome 8
Duration of stay in the emergency department	Within hospital stay, maximum 21 days	Assessed by: Duration of stay in the emergency department
Length of hospital stay	Within hospital stay, maximum 21 days	Assessed by: Length of hospital stay
Post emergency admission (For dyspnea) mortality and rehospitalization	Within 5 years following hospital discharge	Assessed by: Post emergency admission (For dyspnea) mortality and rehospitalization
Proportion of readmissions (all-cause and specific - including hospitalization for acute dyspnea ).	1 month and 1 year post admission for acute dyspnea in the emergency department
Post admission mortality	Within 20 years following hospital discharge	Assessed by: Composite criterion of rehospitalization and/or death following emergency department admission (short and long-term). with outcome 5.
Erroneous etiological diagnosis of dyspnea in the emergency department	Within hospital stay, maximum 21 days	Assessed by: Erroneous etiological diagnosis of dyspnea in the emergency department
In-hospital mortality	Within hospital stay, maximum 21 days	Assessed by: In-hospital mortality
Post admission rehospitalization	Within 20 years following hospital discharge	Assessed by: Composite criterion of rehospitalization and/or death following emergency department admission (short and long-term) with outcome with outcome 4.
Emergency post-admission mortality	Within 20 years following hospital discharge	Assessed by: Composite criterion of mortality and rehospitalization post-admission for acute dyspnea in the emergency department over the long term with outcome 9
Emergency post-admission rehospitalisation	Within 20 years following hospital discharge	Assessed by: Composite criterion of mortality and rehospitalization post-admission for acute dyspnea in the emergency department over the long term outcome 8

Trial Locations

Locations (4)

CHU de Dijon; 🇫🇷 Dijon, France

CHU de Besançon; 🇫🇷 Besançon, France

Hospices civils de Lyon, Groupement Hospitalier Édouard-Herriot; 🇫🇷 Lyon, France

CHRU of Nancy; 🇫🇷 Nancy, France