ISRCTN20993046已完成未知
An International randomised trial of early versus delayed invasive strategies in patients with non-ST segment elevation acute coronary syndromes
Population Health Research Institute (PHRI) (Canada)0 个研究点目标入组 4,000 人开始时间: 2006年11月27日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 4,000
研究概览
简要总结
2009 results in: https://www.ncbi.nlm.nih.gov/pubmed/19458363 (added 10/04/2019)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Patients presenting or admitted to hospital with symptoms suspected to represent an acute coronary syndrome (unstable angina or MI without persistent ST elevation), i.e. clinical history consistent with new onset, or a worsening pattern, of characteristic ischaemic chest pain or ischaemic symptoms occurring at rest or with minimal activity (lasting longer than five minutes or requiring sublingual nitroglycerin for relief of the pain)
- •2. Able to randomise within 24 hours of the onset of the most recent episode of symptoms
- •3. At least two of the three following additional criteria:
- •3.1. Age more than or equal to 60 years, either sex
- •3.2. Troponin T or I or creatine kinase - myocardial bands (CK-MB) above the upper limit of normal for the local institution
- •3.3. Electrocardiogram (ECG) changes compatible with ischaemia (i.e., ST depression at least 1 mm in two contiguous leads or T wave inversion mroe than 3 mm or any dynamic ST shift or transient ST elevation)
- •4. Written informed consent dated and signed
排除标准
- •1. Age less than 21 years
- •2. Not a suitable candidate for revascularisation
- •3. Co-morbid condition with life expectancy less than six months
研究者
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