Safety Study of Subclavian and Internal Jugular Venous Catheterization

Not Applicable

• Conditions: Time to Insertion; Rates of Complications
• Interventions: Device: Central venous catheter

• Registration Number: NCT01196962
• Lead Sponsor: E-DA Hospital

Brief Summary

There is no randomized controlled trial to compare the rates of complications associated with internal jugular and subclavian venous catheterization. The aim of this study is to compare mechanical, infectious, and thrombotic complications of internal jugular and subclavian venous catheterization. An improved understanding of CVC-related risks might help clinicians to choose one approach over the other in specific clinical settings.

Detailed Description

Central venous catheterization is often necessary to treat critically ill patients hospitalized in intensive care units (ICUs). However, this procedure may lead to serious and sometimes life-threatening complications, including mechanical, infectious, or thrombotic complications. The choice of insertion site can influence the incidence and type of such complications. The most frequently used sites for CVC insertion are the internal jugular and the subclavian vein. However, in an individual patient, criteria for choosing one approach over the other remain unclear.

Study Timeline

• Study First Submitted: 2010-09-01
• Study First Submitted QC: 2010-09-07
• Study First Posted: 2010-09-09
• Study Start: 2010-11
• Status Verified: 2011-08
• Last Update Submitted: 2012-11-22
• Last Update Posted: 2012-11-27
• Primary Completion: 2013-12
• Study Completion: 2013-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• admission to ICU
• requiring central venous catheterization
• without contraindications to attempt both jugular and internal jugular access

Exclusion Criteria

• the presence of a central venous catheter at admission
• central venous catheterization within 2 weeks prior to admission
• emergency catheterization for a life-threatening situation
• major blood coagulation disorders
• anatomic defect precluding catheterization at either site
• skin lesions or recent surgery at either site

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Internal jugular vein	Central venous catheter	-

Primary Outcome Measures

Name	Time	Method
Time to completely insertion	1 hour

Secondary Outcome Measures

Name	Time	Method
rates of mechanical, infectious, and thrombotic complications	14 days

Trial Locations

Locations (1)

E-Da hospital; 🇨🇳 Kaohsiung, Taiwan