The effect of Marinol (tetra-9-hydrocannabinol) on the frequency of TLESRs.

Completed

• Registration Number: NL-OMON21968

Brief Summary

/A

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 18

Inclusion Criteria

1. Man,

2. 18-55 years,

Exclusion Criteria

1. Clinical relevant illness two weeks prior to start of study;

2. systemic illness which influence esophageal motility;

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Frequency of transient lower esophageal sfincter relaxations (TLESRs) measured by esophageal manometry up to 3hours postprandially.

Secondary Outcome Measures

Name	Time	Method
Rate of acid reflux episodes measured with pH-metry for 3 hours postprandially, basal lower esophageal sphincter pressure (LESp) measured by manometry.