Clinical Study of Radical Right Hemicolectomy Versus Radical Right Hemicolectomy Combined with Indocyanine Green Fluorescence Imaging Lymphatic Tracer Dissection for the Treatment of Right Colon Cancer

Not Applicable

Recruiting

• Conditions: Colon Cancer
• Interventions: Procedure: radical right hemicolectomy combined with indocyanine green fluorescence imaging lymphatic tracer dissection

• Registration Number: NCT06485609
• Lead Sponsor: Sun Yat-sen University

Brief Summary

The purpose of this study is to explore the clinical outcomes of indocyanine green fluorescence using in laparoscopic radical right hemicolectomy for right colon cancer（T1-T4a N+ M0）

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2024-05-07
• Study First Submitted QC: 2024-07-02
• Study First Posted: 2024-07-03
• Study Start: 2024-08-10
• Status Verified: 2025-01
• Last Update Submitted: 2025-01-15
• Last Update Posted: 2025-01-17
• Primary Completion: 2027-06-01
• Study Completion: 2031-07-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 1200

Inclusion Criteria

• 1. Age between 18 and 75 years old 2. Confirmed adenocarcinoma cancer pathologically 3. Location of tumor: from the cecum to the right third of the transverse colon 4. CT showed right colon cancer: T1-T4a N+ M0 5. ASA scores I-III 6. ECOG (Eastern Cooperative Oncology Group) scale performance status of 0 or 1 7. Patient or family member, able to understand the study protocol and willing to participate in the study, providing written informed consent

Exclusion Criteria

• 1. Simultaneous or heterochronic multiple primary colon cancer 2. Patients with intestinal obstruction, intestinal perforation, intestinal bleeding, etc. requiring emergency surgery 3. Unsuitable for laparoscopic surgery (e.g., extensive adhesions due to previous major abdominal surgery; unsuitable for pneumoperitoneum for various reasons, etc.) 4. Pregnant or lactating women 5. Have a history of serious mental illness 6. History of iodine allergy 7. History of other malignant diseases within the last five years 8. History of prior neoadjuvant chemotherapy or radiation therapy 9. History of unstable angina or myocardial infarction within the last 6 months 10. History of continuous systemic corticosteroid use within one month

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
radical right hemicolectomy combined with indocyanine green fluorescence imaging lymphatic tracer di	radical right hemicolectomy combined with indocyanine green fluorescence imaging lymphatic tracer dissection	-

Primary Outcome Measures

Name	Time	Method
Disease-free survival rate	3 years

Secondary Outcome Measures

Name	Time	Method
Number of lymph nodes cleared	Immediately after surgery

Trial Locations

Locations (1)

The Sixth Affiliated Hospital, Sun Yat-sen University; 🇨🇳 Guangzhou, China