Recurrence Rate of Mini-SLET vs. Limbal-Conjunctival Autograft in Primary Pterygium Excision
- Conditions
- Pterygium of Conjunctiva and Cornea
- Interventions
- Procedure: Pterygium Excision
- Registration Number
- NCT03363282
- Lead Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
- Brief Summary
To study the efficacy and safety of amniotic membrane transplantation as an adjunctive therapy after surgical excision of primary pterygium and compare the clinical outcomes with conjunctival autograft
- Detailed Description
Prospective Randomized Blind Clinical Trial
Sixty-four eyes of 64 patients with primary nasal pterygium have been operated by two surgeons (E. G-H, A. N-C). All patients are randomized to undergo Mini-SLET or limbal-conjunctival autograft transplantation as an adjuvant therapy after pterygium excision.
Four eyes were treated with Mini-SLET(group 1), and 26 eyes have been operated with conjunctival autograft (group 2). Patients will be followed up at 1 day, 1 week, 1, 3, 6, 9 and 12 months postoperation. The main outcome measurement was a recurrence rate after surgery.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 57
- Patients with primary nasal pterygium > 2mm
- Pregnant
- Previous ocular surgery
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Mini-SLET Pterygium Excision Simple Limbal Epithelial Transplantation Limbal-Conjunctival Autograft Pterygium Excision Patients treated with limbal-conjunctival autograft
- Primary Outcome Measures
Name Time Method Recurrence rate one day Regrowth of pterygium
- Secondary Outcome Measures
Name Time Method