A single centre, open label, pilot study evaluating the effect of intra-articular hyaluronic acid injection on pain and functionality when injected into the ankle (tibio-talar and sub-talar) joint in patients with haemophilic arthropathy

Oxford University Hospitals NHS Foundation Trust0 个研究点目标入组 24 人开始时间: 2018年9月4日最近更新: 2022年8月22日

适应症

试验速览

2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35905300/ (added 01/08/2022)

•1. Written informed consent obtained before any study related activity
•2. Adult male (age 18 years or older) with haemophilia A or haemophilia B of any severity, including those with inhibitors
•3. MRI ankle changes consistent with haemophilic arthropathy – showing synovitic and/or degenerative changes to one or both ankle joints

•1. The patient has evidence of infection, including those patients taking antibiotic therapy
•2. The patient has known inflammatory joint disease, including crystal disease
•3. The patient has received an intra-articular steroid injection within the preceding 6 months
•4. The patient is known to be allergic to any of the excipients of Ostenil Plus

发起方

Oxford University Hospitals NHS Foundation Trust