Clinical and Economic Impact of Interventions by a Clinical Pharmacist on Antibiotic Use on Surgical Wards
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 779
- 试验地点
- 2
- 主要终点
- overall duration of antibiotic therapy during study period
研究概览
简要总结
The purpose of this study is to establish the impact of a pharmacist's recommendations regarding choice, dosing and duration of antibiotic therapy on quality and cost of antibiotic treatment on surgical wards.
详细描述
Inappropriate or incorrect use of antibacterials exerts selection pressure on pathogens potentiating emergence of resistance, puts patients at risk for unnecessary adverse drug reactions and potentially prolongs the length of stay in hospital thus increasing healthcare costs.
In an effort to improve the quality of antibiotic drug therapy on surgical wards of a large university hospital, specific consulting by a clinical pharmacist was established.
The objective of this study is to assess the impact of pharmaceutical consulting on the quality and costs of antibiotic use in surgical wards.
Comparison:
Within a control period the current pattern of antibiotic use is monitored. During the intervention period, the impact of the interventions made by the clinical pharmacist on antibiotic use is examined. One ward serves as a parallel control group; no intervention is being made on this ward throughout this study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •female and male patients receiving antibiotics for a proven or suspected infection on designated surgical wards
排除标准
- •patients under 18
- •patients unable or unwilling to consent to their data being evaluated
- •patients receiving antibiotics perioperatively as prophylaxis
- •patients receiving antibiotics for less than 48hrs
结局指标
主要结局
overall duration of antibiotic therapy during study period
时间窗: Feb 2008
次要结局
- iv to oral switch(Feb 2008)
- compliance of treatment with hospital formulary for antibiotic therapy(Feb 2008)
- cost of antibiotic therapy(Feb 2008)
- number and duration of therapy with antibiotics with redundant spectra(Feb 2008)
研究者
Alexandra Weber
Pharmacist
Ludwig-Maximilians - University of Munich