Clinical and Economic Impact of Interventions by a Clinical Pharmacist on Antibiotic Use on Surgical Wards
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Bacterial Infections
- Sponsor
- Ludwig-Maximilians - University of Munich
- Enrollment
- 779
- Locations
- 1
- Primary Endpoint
- overall duration of antibiotic therapy during study period
- Status
- Completed
- Last Updated
- 12 years ago
Overview
Brief Summary
The purpose of this study is to establish the impact of a pharmacist's recommendations regarding choice, dosing and duration of antibiotic therapy on quality and cost of antibiotic treatment on surgical wards.
Detailed Description
Inappropriate or incorrect use of antibacterials exerts selection pressure on pathogens potentiating emergence of resistance, puts patients at risk for unnecessary adverse drug reactions and potentially prolongs the length of stay in hospital thus increasing healthcare costs. In an effort to improve the quality of antibiotic drug therapy on surgical wards of a large university hospital, specific consulting by a clinical pharmacist was established. The objective of this study is to assess the impact of pharmaceutical consulting on the quality and costs of antibiotic use in surgical wards. Comparison: Within a control period the current pattern of antibiotic use is monitored. During the intervention period, the impact of the interventions made by the clinical pharmacist on antibiotic use is examined. One ward serves as a parallel control group; no intervention is being made on this ward throughout this study.
Investigators
Alexandra Weber
Pharmacist
Ludwig-Maximilians - University of Munich
Eligibility Criteria
Inclusion Criteria
- •female and male patients receiving antibiotics for a proven or suspected infection on designated surgical wards
Exclusion Criteria
- •patients under 18
- •patients unable or unwilling to consent to their data being evaluated
- •patients receiving antibiotics perioperatively as prophylaxis
- •patients receiving antibiotics for less than 48hrs
Outcomes
Primary Outcomes
overall duration of antibiotic therapy during study period
Time Frame: Feb 2008
Secondary Outcomes
- iv to oral switch(Feb 2008)
- compliance of treatment with hospital formulary for antibiotic therapy(Feb 2008)
- cost of antibiotic therapy(Feb 2008)
- number and duration of therapy with antibiotics with redundant spectra(Feb 2008)